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Neuroprotective effects of furopyrazole derivative of benzylindazole analogs on C2 ceramide-induced apoptosis in cultured cortical neurons

Author
LIN, Yi-Chien1 ; CHOU, Li-Chen1 ; CHEN, Sheng-Chih1 ; KUO, Sheng-Chu1 ; HUANG, Li-Jiau1 ; GEAN, Po-Wu2
[1] Graduate Institute of Pharmaceutic Chemistry, China Medical University, Taichung 404, Taiwan, Province of China
[2] Department of Pharmacology, Center for Gene Regulation and Signal Transduction Research, National Cheng-Kung University, Tainan 701, Taiwan, Province of China
Source

Bioorganic & medicinal chemistry letters (Print). 2009, Vol 19, Num 12, pp 3225-3228, 4 p

ISSN
0960-894X
Scientific domain
Biochemistry, molecular biology, biophysics; Pharmacology drugs
Publisher
Elsevier, Amsterdam
Publication country
Netherlands
Document type
Article
Language
English
Author keyword
Apoptosis Benzylindazole analogs Ceramide Neurodegenerative diseases
Keyword (fr)
Antiapoptotique Apoptose Culture cellulaire Céramide Dérivé de l'indazole Dérivé du benzène Dérivé du furane In vitro Maladie dégénérative Mécanisme action Neurone Neuroprotecteur Pathologie du système nerveux Relation structure activité Furopyrazole
Keyword (en)
Antiapoptotic agent Apoptosis Cell culture Ceramide Indazole derivatives Benzene derivatives Furan derivatives In vitro Degenerative disease Mechanism of action Neuron Neuroprotective agent Nervous system diseases Structure activity relation
Keyword (es)
Antiapoptosis Apoptosis Cultivo celular Cerámida Indazol derivado Benceno derivado Furano derivado In vitro Enfermedad degenerativa Mecanismo acción Neurona Neuroprotector Sistema nervioso patología Relación estructura actividad
Classification
Pascal
002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02B Neuropharmacology / 002B02B10 Neuroprotective agent

Discipline
Pharmacological treatments
Origin
Inist-CNRS
Database
PASCAL
INIST identifier
21589325

Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS

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