Poly(ADP-Ribose) Polymerase-1 Inhibitor Treatment Regresses Autochthonous Brca2/p53-Mutant Mammary Tumors In vivo and Delays Tumor Relapse in Combination with Carboplatin
- Author
- HAY, Trevor1 ; MATTHEW, James R1 ; CLARKE, Alan R1 ; PIETZKA, Lucie1 ; LAU, Alan3 ; CRANSTON, Aaron3 ; NYGREN, Anders O. H4 ; DOUGLAS-JONES, Anthony2 ; SMITH, Graeme C. M3 ; MARTIN, Niall M. B3 ; O'CONNOR, Mark3
[1] Department of Genetics, School of Biosciences, Cardiff University, Cardiff, United Kingdom
[2] Department of Pathology, Wales College of Medicine, School of Medicine, Cardiff University, Cardiff, United Kingdom
[3] KuDOS Pharmaceuticals Ltd., Cambridge, United Kingdom
[4] MRC-Holland, Amsterdam, Netherlands - Source
Cancer research (Chicago, Ill.). 2009, Vol 69, Num 9, pp 3850-3855, 6 p ; ref : 23 ref
- CODEN
- CNREA8
- ISSN
- 0008-5472
- Scientific domain
- Medical oncology; Pharmacology drugs
- Publisher
- American Association for Cancer Research, Philadelphia, PA
- Publication country
- United States
- Document type
- Article
- Language
- English
- Keyword (fr)
- Anticancéreux Association médicamenteuse Autochtone Carboplatine Glande mammaire Gène BRCA2 Gène TP53 Gène suppresseur tumeur In vivo Inhibiteur Mutation NAD+ ADP-ribosyltransferase Récidive Traitement Tumeur maligne Gène p53 Cancer Enzyme Glycosyltransferases Pentosyltransferases Platine II Complexe Transferases
- Keyword (en)
- Antineoplastic agent Drug combination Autochthonous Carboplatin Mammary gland BRCA2 gene TP53 Gene Tumor suppressor gene In vivo Inhibitor Mutation NAD+ ADP-ribosyltransferase Relapse Treatment Malignant tumor Cancer Enzyme Glycosyltransferases Pentosyltransferases Platinum II Complexes Transferases
- Keyword (es)
- Anticanceroso Asociación medicamentosa Autóctono Carboplatino Glándula mamaria Gen BRCA2 Gen TP53 Gen supresor tumor In vivo Inhibidor Mutación NAD+ ADP-ribosyltransferase Recaida Tratamiento Tumor maligno Cáncer Enzima Glycosyltransferases Pentosyltransferases Platino II Complejo Transferases
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02R Antineoplastic agents
- Discipline
- Pharmacological treatments Tumours
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 21718538
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1158/0008-5472.CAN-08-2388 
https://dx.doi.org/10.1158/0008-5472.CAN-08-2388
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