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Poly(ADP-Ribose) Polymerase-1 Inhibitor Treatment Regresses Autochthonous Brca2/p53-Mutant Mammary Tumors In vivo and Delays Tumor Relapse in Combination with Carboplatin

Author
HAY, Trevor1 ; MATTHEW, James R1 ; CLARKE, Alan R1 ; PIETZKA, Lucie1 ; LAU, Alan3 ; CRANSTON, Aaron3 ; NYGREN, Anders O. H4 ; DOUGLAS-JONES, Anthony2 ; SMITH, Graeme C. M3 ; MARTIN, Niall M. B3 ; O'CONNOR, Mark3
[1] Department of Genetics, School of Biosciences, Cardiff University, Cardiff, United Kingdom
[2] Department of Pathology, Wales College of Medicine, School of Medicine, Cardiff University, Cardiff, United Kingdom
[3] KuDOS Pharmaceuticals Ltd., Cambridge, United Kingdom
[4] MRC-Holland, Amsterdam, Netherlands
Source

Cancer research (Chicago, Ill.). 2009, Vol 69, Num 9, pp 3850-3855, 6 p ; ref : 23 ref

CODEN
CNREA8
ISSN
0008-5472
Scientific domain
Medical oncology; Pharmacology drugs
Publisher
American Association for Cancer Research, Philadelphia, PA
Publication country
United States
Document type
Article
Language
English
Keyword (fr)
Anticancéreux Association médicamenteuse Autochtone Carboplatine Glande mammaire Gène BRCA2 Gène TP53 Gène suppresseur tumeur In vivo Inhibiteur Mutation NAD+ ADP-ribosyltransferase Récidive Traitement Tumeur maligne Gène p53 Cancer Enzyme Glycosyltransferases Pentosyltransferases Platine II Complexe Transferases
Keyword (en)
Antineoplastic agent Drug combination Autochthonous Carboplatin Mammary gland BRCA2 gene TP53 Gene Tumor suppressor gene In vivo Inhibitor Mutation NAD+ ADP-ribosyltransferase Relapse Treatment Malignant tumor Cancer Enzyme Glycosyltransferases Pentosyltransferases Platinum II Complexes Transferases
Keyword (es)
Anticanceroso Asociación medicamentosa Autóctono Carboplatino Glándula mamaria Gen BRCA2 Gen TP53 Gen supresor tumor In vivo Inhibidor Mutación NAD+ ADP-ribosyltransferase Recaida Tratamiento Tumor maligno Cáncer Enzima Glycosyltransferases Pentosyltransferases Platino II Complejo Transferases
Classification
Pascal
002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02R Antineoplastic agents

Pascal
002 Biological and medical sciences / 002B Medical sciences / 002B04 Tumors

Discipline
Pharmacological treatments Tumours
Origin
Inist-CNRS
Database
PASCAL
INIST identifier
21718538

Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS

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