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Population Pharmacokinetics of Tacrolimus in Pediatric Hematopoietic Stem Cell Transplant Recipients: New Initial Dosage Suggestions and a Model-Based Dosage Adjustment Tool

Author
WALLIN, Johan E1 ; FRIBERG, Lena E1 ; FASTH, Anders2 ; STAATZ, Christine E1 3
[1] Division of Pharmacokinetics and Drug Therapy, Uppsala University, Uppsala, Sweden
[2] Department of Paediatrics, University of Gothenburg, Gothenburg, Sweden
[3] School of Pharmacy, University of Queensland, Brisbane, Australia
Source

Therapeutic drug monitoring. 2009, Vol 31, Num 4, pp 457-466, 10 p ; ref : 43 ref

CODEN
TDMODV
ISSN
0163-4356
Scientific domain
Pharmacology drugs
Publisher
Lippincott Williams & Wilkins, Hagerstown, MD
Publication country
United States
Document type
Article
Language
English
Author keyword
Bayesian forecasting dosage prediction pediatric hematopoietic stem cell transplant population pharmacokinetics tacrolimus
Keyword (fr)
Adaptation posologie Analyse statistique Cellule hématopoïétique Cellule souche Enfant Facteur prédictif Greffe Immunodépresseur Immunomodulateur Modèle Nourrisson Pharmacocinétique de la population Prédiction Prévision Pédiatrie Receveur Tacrolimus Ajustement posologie Homme Inhibiteur de la calcineurine Inhibiteur synthèse protéique Lactone Macrolide
Keyword (en)
Dosage adjustment Statistical analysis Hematopoietic cell Stem cell Child Predictive factor Graft Immunosuppressive agent Immunomodulator Models Infant Population pharmacokinetics Prediction Forecasting Pediatrics Recipient Tacrolimus Human Calcineurin inhibitor Protein synthesis inhibitor Lactone Macrolide
Keyword (es)
Adaptación posología Análisis estadístico Célula hematopoyética Célula primitiva Niño Factor predictivo Injerto Inmunodepresor Inmunomodulador Modelo Lactante Farmacocinética población Predicción Previsión Pediatría Receptor Tacrolimús Hombre Inhibidor calcineurina Inhibidor síntesis proteica Lactona Macrólido
Classification
Pascal
002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments

Discipline
General pharmacology
Origin
Inist-CNRS
Database
PASCAL
INIST identifier
21797838

Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS

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