Ligand-Independent Androgen Receptor Variants Derived from Splicing of Cryptic Exons Signify Hormone-Refractory Prostate Cancer
- Author
- RONG HU1 ; DUNN, Thomas A1 ; BOVA, G. Steven1 2 3 ; JUN LUO1 2 ; SHUANZENG WEI1 ; ISHARWAL, Sumit1 ; VELTRI, Robert W1 ; HUMPHREYS, Elizabeth1 ; HAN, Misop1 ; PARTIN, Alan W1 3 ; VESSELLA, Robert L4 ; ISAACS, William B1 2 3
[1] Department of Urology, The Johns Hopkins University School of Medicine, Baltimore, Maryland, United States
[2] Department of Oncology, The Johns Hopkins University School of Medicine, Baltimore, Maryland, United States
[3] Department of Pathology, The Johns Hopkins University School of Medicine, Baltimore, Maryland, United States
[4] Department of Urology, University of Washington and the Puget Sound VA Medical Center, Seattle, Washington, United States - Source
Cancer research (Chicago, Ill.). 2009, Vol 69, Num 1, pp 16-22, 7 p ; ref : 20 ref
- CODEN
- CNREA8
- ISSN
- 0008-5472
- Scientific domain
- Medical oncology; Pharmacology drugs
- Publisher
- American Association for Cancer Research, Philadelphia, PA
- Publication country
- United States
- Document type
- Article
- Language
- English
- Keyword (fr)
- Androgène Cancer de la prostate Cryptique Epissage Exon Génotype Hormonoindépendance Ligand Résistance traitement Traitement hormonal Variabilité génétique Variant Cancer Hormone stéroïde sexuelle Pathologie de l'appareil génital mâle Pathologie de l'appareil urinaire Pathologie de la prostate Tumeur maligne
- Keyword (en)
- Androgen Prostate cancer Cryptic Splicing Exon Genotype Hormonoindependence Ligand Treatment resistance Hormone therapy Genetic variability Variant Cancer Sex steroid hormone Male genital diseases Urinary system disease Prostate disease Malignant tumor
- Keyword (es)
- Andrógeno Cáncer de la próstata Críptico Empalme Exón Genotipo Hormonoindependencia Ligando Resistencia tratamiento Hormonoterapia Variabilidad genética Variante Cáncer Hormona esteroide sexual Aparato genital macho patología Aparato urinario patología Prostata patología Tumor maligno
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02R Antineoplastic agents
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B14 Nephrology. Urinary tract diseases / 002B14D Tumors of the urinary system / 002B14D02 Urinary tract. Prostate gland
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B20 Gynecology. Andrology. Obstetrics / 002B20B Male genital diseases / 002B20B02 Tumors
- Discipline
- Gynecology. Andrology. Obstetrics Nephrology. Urinary tract diseases Pharmacological treatments Tumours
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 21883664
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1158/0008-5472.CAN-08-2764 
https://dx.doi.org/10.1158/0008-5472.CAN-08-2764
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