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Hierarchical Maintenance of MLL Myeloid Leukemia Stem Cells Employs a Transcriptional Program Shared with Embryonic Rather Than Adult Stem Cells

Author
SOMERVAILLE, Tim C. P1 4 ; MATHENY, Christina J1 ; SPENCER, Gary J4 ; IWASAKI, Masayuki1 ; RINN, John L2 ; WITTEN, Daniela M3 ; CHANG, Howard Y2 ; SHURTLEFF, Sheila A5 ; DOWNING, James R5 ; CLEARY, Michael L1
[1] Department of Pathology, Stanford University, Stanford, CA 94305, United States
[2] Program in Epithelial Biology, Stanford University, Stanford, CA 94305, United States
[3] Department of Statistics, Stanford University, Stanford, CA 94305, United States
[4] Cancer Research UK Leukaemia Biology Group, Paterson Institute for Cancer Research, University of Manchester, Manchester M20 4BX, United Kingdom
[5] Department of Pathology, St. Jude Children's Research Hospital, Memphis, TN 38105, United States
Source

Cell stem cell. 2009, Vol 4, Num 2, pp 129-140, 12 p ; ref : 1 p.1/4

ISSN
1934-5909
Scientific domain
Cell biology, histology
Publisher
Cell Press, Cambridge, MA
Publication country
United States
Document type
Article
Language
English
Keyword (fr)
Adulte Cellule myéloïde Cellule souche Leucémie myéloïde chronique Programme Transcription Cancer Homme Hémopathie maligne Syndrome myéloprolifératif
Keyword (en)
Adult Myeloid cell Stem cell Chronic myelogenous leukemia Program Transcription Cancer Human Malignant hemopathy Myeloproliferative syndrome
Keyword (es)
Adulto Célula mieloide Célula primitiva Leucemia mieloidea crónica Programa Transcripción Cáncer Hombre Hemopatía maligna Mieloproliferativo síndrome
Classification
Pascal
002 Biological and medical sciences / 002A Fundamental and applied biological sciences. Psychology / 002A04 Molecular and cellular biology / 002A04C Molecular genetics / 002A04C05 Transcription. Transcription factor. Splicing. Rna processing

Pascal
002 Biological and medical sciences / 002B Medical sciences / 002B19 Hematologic and hematopoietic diseases / 002B19B Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis

Discipline
Blood diseases Molecular and cell biology
Origin
Inist-CNRS
Database
PASCAL
INIST identifier
21901944

Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS

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