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Factor H-related protein 1 (CFHR-1) inhibits complement C5 convertase activity and terminal complex formation

Author
HEINEN, Stefan1 ; HARTMANN, Andrea1 ; MIHLAN, Michael1 ; SCHLÖTZER-SCHREHARDT, Ursula3 ; ZIPFEL, Peter F1 4 ; SKERKA, Christine1 ; LAUER, Nadine1 ; WIEHL, Ulrike1 ; DAHSE, Hans-Martin1 ; SCHIRMER, Sylvia1 ; GROPP, Katharina1 ; ENGHARDT, Tina1 ; WALLICH, Reinhard2 ; HALBICH, Steffi1
[1] Department of Infection Biology, Leibniz Institute for Natural Product Research and Infection Biology, Hans Knöll Institute, Jena, Germany
[2] Institute for Immunology, University of Heidelberg, Heidelberg, Germany
[3] Department of Ophthalmology, University of Erlangen-Nürnberg, Erlangen, Germany
[4] Friedrich-Schiller-University, Jena, Germany
Source

Blood. 2009, Vol 114, Num 12, pp 2439-2447, 9 p ; ref : 39 ref

ISSN
0006-4971
Scientific domain
Medical oncology; Hematology
Publisher
Americain Society of Hematology, Washington, DC
Publication country
United States
Document type
Article
Language
English
Keyword (fr)
Activité biologique Classical-complement-pathway C3/C5 convertase Complément C5 Hématologie Inhibiteur Protéine Facteur H Enzyme Hydrolases Peptidases Serine endopeptidases
Keyword (en)
Biological activity Classical-complement-pathway C3/C5 convertase Complement C5 Hematology Inhibitor Protein Factor H Enzyme Hydrolases Peptidases Serine endopeptidases
Keyword (es)
Actividad biológica Classical-complement-pathway C3/C5 convertase Complemento C5 Hematología Inhibidor Proteína Enzima Hydrolases Peptidases Serine endopeptidases
Classification
Pascal
002 Biological and medical sciences / 002B Medical sciences / 002B19 Hematologic and hematopoietic diseases

Discipline
Blood diseases
Origin
Inist-CNRS
Database
PASCAL
INIST identifier
21955486

Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS

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