Push-pull benzothiazole derivatives as probes for detecting β-amyloid plaques in Alzheimer's brains
- Author
- ONO, Masahiro1 ; HAYASHI, Shun1 ; KIMURA, Hiroyuki1 ; KAWASHIMA, Hidekazu2 ; NAKAYAMA, Morio3 ; SAJI, Hideo1
[1] Graduate School of Pharmaceutical Sciences, Kyoto University, 46-29 Yoshida Shimoadachi-cho, Sakyo-ku, Kyoto 606-8501, Japan
[2] Graduate School of Medicine, Kyoto University, Shogoin Kawahara-cho, Kyoto 606-8507, Japan
[3] Graduate School of Biomedical Sciences, Nagasaki University, 1-14 Bunkyo-machi, Nagasaki 852-8521, Japan - Source
Bioorganic & medicinal chemistry. 2009, Vol 17, Num 19, pp 7002-7007, 6 p ; ref : 21 ref
- ISSN
- 0968-0896
- Scientific domain
- Biochemistry, molecular biology, biophysics; Pharmacology drugs
- Publisher
- Elsevier, Amsterdam
- Publication country
- Netherlands
- Document type
- Article
- Language
- English
- Author keyword
- Alzheimer's disease Imaging Push-pull dye β-Amyloid
- Keyword (fr)
- Animal Démence d'Alzheimer Dérivé du benzothiazole Fixation biologique Formation image In vitro In vivo Interaction moléculaire Protéine amyloïde β Souris Spectrométrie fluorescence Synthèse chimique Système nerveux central Ethylène-1,1-dicarbonitrile(2-[4-(2-[6-diméthylaminobenzothiazol-2-yl]vinyl)phényl]) Ethylène-1,1-dicarbonitrile(2-[6-diméthylaminobenzothiazol-2-yl]) Malononitrile dérivé Maladie dégénérative Mammalia Pathologie de l'encéphale Pathologie du système nerveux central Pathologie du système nerveux Rodentia Vertebrata
- Keyword (en)
- Animal Alzheimer disease Benzothiazole derivatives Biological fixation Imaging In vitro In vivo Molecular interaction β Amyloid protein Mouse Fluorescence spectrometry Chemical synthesis Central nervous system Degenerative disease Mammalia Cerebral disorder Central nervous system disease Nervous system diseases Rodentia Vertebrata
- Keyword (es)
- Animal Demencia Alzheimer Benzotiazol derivado Fijación biológica Formación imagen In vitro In vivo Interacción molecular Proteína amiloide β Ratón Espectrometría fluorescencia Síntesis química Sistema nervioso central Enfermedad degenerativa Mammalia Encéfalo patología Sistema nervosio central patología Sistema nervioso patología Rodentia Vertebrata
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02B Neuropharmacology / 002B02B02 Psychoanaleptics: cns stimulant, antidepressant agent, nootropic agent, mood stabilizer..., (alzheimer disease)
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B24 Investigative techniques, diagnostic techniques (general aspects) / 002B24O Pathology. Cytology. Biochemistry. Spectrometry. Miscellaneous investigative techniques / 002B24O14 Miscellaneous. Technology
- Francis
- 770 Psychology. Psychoanalysis. Psychiatry / 770-E Psychopharmacology / 770-E02 Psychoanaleptics: cns stimulant, antidepressant agent, nootropic agent, mood stabilizer…
- Discipline
- Pharmacological treatments Psychopathology. Psychiatry. Clinical psychology Scanning and diagnostic techniques
- Origin
- Inist-CNRS
- Database
- FRANCIS ; PASCAL
- INIST identifier
- 21960788
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1016/j.bmc.2009.08.032 
https://dx.doi.org/10.1016/j.bmc.2009.08.032
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