Overview of molecular testing in non-small-cell lung cancer: mutational analysis, gene copy number, protein expression and other biomarkers of EGFR for the prediction of response to tyrosine kinase inhibitors
- Author
- JOHN, T1 ; LIU, G1 ; TSAO, M.-S1
[1] University Health Network, Princess Margaret Hospital Site, Ontario Cancer Institute, University of Toronto, Toronto, Ontario, Canada - Issue title
- The role of genetic testing in the prediction of response to EGFR inhibitors in NSCLC
- Author (monograph)
- HIRSCH, Fred R (Editor)1
[1] Department of Medical Oncology, University of Colorado Cancer Center, Aurora, CO, United States - Source
Oncogene (Basingstoke). 2009, Vol 28 ; S14-S23 ; SUP1 ; ref : 3 p.1/4
- ISSN
- 0950-9232
- Scientific domain
- Cell biology, histology; Medical oncology; Genetics
- Publisher
- Nature Publishing Group, Basingstoke
- Publication country
- United Kingdom
- Document type
- Article
- Language
- English
- Author keyword
- biomarker erlotinib gefitinib polymerase chain reaction survival
- Keyword (fr)
- Anticancéreux Carcinogenèse Carcinome non petite cellule bronchopulmonaire Erlotinib Gène Géfitinib Inhibiteur Marqueur biologique Mutation Nombre copie Protein-tyrosine kinase Protéine Prédiction Réaction chaîne polymérase Survie Cancer Enzyme Pathologie de l'appareil respiratoire Pathologie des bronches Pathologie des poumons Transferases Tumeur maligne
- Keyword (en)
- Antineoplastic agent Carcinogenesis non-small cell lung carcinoma Erlotinib Gene Gefitinib Inhibitor Biological marker Mutation Copy number Protein-tyrosine kinase Protein Prediction Polymerase chain reaction Survival Cancer Enzyme Respiratory disease Bronchus disease Lung disease Transferases Malignant tumor
- Keyword (es)
- Anticanceroso Carcinogénesis Carcinoma no pequeňa célula bronchopulmonar Erlotinib Gen Gefitinib Inhibidor Marcador biológico Mutación Número copia Protein-tyrosine kinase Proteína Predicción Reacción cadena polimerasa Sobrevivencia Cáncer Enzima Aparato respiratorio patología Bronquio patología Pulmón patología Transferases Tumor maligno
- Classification
- Pascal
- 002 Biological and medical sciences / 002A Fundamental and applied biological sciences. Psychology / 002A04 Molecular and cellular biology / 002A04H Cell physiology / 002A04H04 Cell transformation and carcinogenesis. Action of oncogenes and antioncogenes
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B11 Pneumology / 002B11A Tumors of the respiratory system and mediastinum
- Discipline
- Molecular and cell biology Pulmonology
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 21975762
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1038/onc.2009.197 
https://dx.doi.org/10.1038/onc.2009.197
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