Development and validation of a high-performance liquid chromatography/tandem mass spectrometry method for the determination of artemether and its active metabolite dihydroartemisinin in human plasma
- Author
- LIUSHENG HUANG1 ; JAYEWARDENE, Anura L1 ; XIAOHUA LI2 ; MARZAN, Florence1 ; LIZAK, Patricia S1 ; AWEEKA, Francesca T1
[1] Department of Clinical Pharmacy, School of Pharmacy, University of California, San Francisco, CA 94110, United States
[2] Department of Biopharmaceutical Sciences, School of Pharmacy, University of California, San Francisco, CA 94110, United States - Source
Journal of pharmaceutical and biomedical analysis. 2009, Vol 50, Num 5, pp 959-965, 7 p ; ref : 17 ref
- CODEN
- JPBADA
- ISSN
- 0731-7085
- Scientific domain
- Medical laboratory techniques; Pharmacology drugs
- Publisher
- Elsevier, Amsterdam
- Publication country
- Netherlands
- Document type
- Article
- Language
- English
- Author keyword
- Artemether Artemisinin Dihydroartemisinin LC-MS/MS Solid phase extraction
- Keyword (fr)
- Analyse quantitative Antipaludique Antiparasitaire Artémisinine Artéméther Chromatographie HPLC Détermination Développement Endoperoxyde Enrichissement chimique Extraction SPE Homme Hémiacétal Lactone Liquide biologique Métabolite Plasma sanguin Préparation échantillon Sesquiterpène Spectrométrie masse tandem Terpénoïde Validation Dihydroartémisinine dérivé Dérivé de l'artémisinine LC MS MS
- Keyword (en)
- Quantitative analysis Antimalarial Parasiticide Artemisinin Artemether HPLC chromatography Determination Development Endoperoxide Chemical enrichment Solid phase extraction Human Hemiacetal Lactone Biological fluid Metabolite Blood plasma Sample preparation Sesquiterpenes Mass spectrometry MS/MS Terpenoid Validation
- Keyword (es)
- Análisis cuantitativo Antipalúdico Antiparasitario Artemisinina Artemetero Cromatografía HPLC Determinación Desarrollo Endoperóxido Enriquecimiento químico Extracción SPE Hombre Hemiacetal Lactona Líquido biológico Metabolito Plasma sanguíneo Preparación muestreo Sesquiterpeno Espectrometría masa en tándem Terpenoide Validación
- Classification
- Pascal
- 002 Biological and medical sciences / 002A Fundamental and applied biological sciences. Psychology / 002A02 Analytical, structural and metabolic biochemistry
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02A General pharmacology / 002B02A02 Analysis
- Discipline
- Analytical, structural and metabolic biochemistry General pharmacology
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 22013368
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1016/j.jpba.2009.06.051 
https://dx.doi.org/10.1016/j.jpba.2009.06.051
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