Genetic Alterations in the Phosphoinositide 3-Kinase/Akt Signaling Pathway Confer Sensitivity of Thyroid Cancer Cells to Therapeutic Targeting of Akt and Mammalian Target of Rapamycin
- Author
- DINGXIE LIU1 ; PENG HOU1 ; ZHI LIU1 ; GUOJUN WU2 ; MINGZHAO XING1
[1] Division of Endocrinology and Metabolism, the Johns Hopkins University School of Medicine, Baltimore, Maryland, United States
[2] Breast Cancer Program, Karmanos Cancer Institute, Detroit, Michigan, United States - Source
Cancer research (Chicago, Ill.). 2009, Vol 69, Num 18, pp 7311-7319, 9 p ; ref : 47 ref
- CODEN
- CNREA8
- ISSN
- 0008-5472
- Scientific domain
- Medical oncology; Pharmacology drugs
- Publisher
- American Association for Cancer Research, Philadelphia, PA
- Publication country
- United States
- Document type
- Article
- Language
- English
- Keyword (fr)
- 1-Phosphatidylinositol 3-kinase Akt protein kinase Altération Cancer de la thyroïde Cellule tumorale Génétique Protéine mTOR Sensibilité Thérapeutique ciblée Transduction signal Voie de signalisation Cancer Endocrinopathie Enzyme Pathologie de la thyroïde Transferases Tumeur maligne
- Keyword (en)
- 1-Phosphatidylinositol 3-kinase Akt protein kinase Alteration Thyroid cancer Tumor cell Genetics Mammalian target of rapamycin Sensitivity Targeted therapy Signal transduction Signaling pathway Cancer Endocrinopathy Enzyme Thyroid diseases Transferases Malignant tumor
- Keyword (es)
- 1-Phosphatidylinositol 3-kinase Akt protein kinase Alteración Cáncer de la tiroides Célula tumoral Genética Proteína mTOR Sensibilidad Terapéutica dirigida Transducción señal Cáncer Endocrinopatía Enzima Tiroides patología Transferases Tumor maligno
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02R Antineoplastic agents
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B21 Endocrinopathies / 002B21C Thyroid. Thyroid axis (diseases) / 002B21C01 Non tumoral diseases. Target tissue resistance. Benign neoplasms
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B21 Endocrinopathies / 002B21C Thyroid. Thyroid axis (diseases) / 002B21C02 Malignant tumors
- Discipline
- Endocrinopathies Pharmacological treatments Tumours
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 22020440
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1158/0008-5472.CAN-09-1077 
https://dx.doi.org/10.1158/0008-5472.CAN-09-1077
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