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Podocytes produce homeostatic chemokine stromal cell-derived factor-1/CXCL12, which contributes to glomerulosclerosis, podocyte loss and albuminuria in a mouse model of type 2 diabetes

Author
SAYYED, S. G1 ; HÄGELE, H1 ; KULKARNI, O. P1 ; ENDLICH, K2 ; SEGERER, S3 4 ; EULBERG, D5 ; KLUSSMANN, S5 ; ANDERS, H.-J1
[1] Nephrological Center, Medizinische Poliklinik, Klinikum der Universität München-Innenstadt, Pettenkoferstr. 8a, 80336 München, Germany
[2] Department of Anatomy and Cell Biology, University of Greifswald, Greifswald, Germany
[3] Division of Nephrology, University Hospital, Zürich, Switzerland
[4] Institute of Anatomy, University of Zürich, Zürich, Switzerland
[5] NOXXON Pharma, Berlin, Germany
Source

Diabetologia (Berlin). 2009, Vol 52, Num 11, pp 2445-2454, 10 p ; ref : 50 ref

ISSN
0012-186X
Scientific domain
Endocrinology; Nutrition, obesity, metabolic disorders
Publisher
Springer, Heidelberg
Publication country
Germany
Document type
Article
Language
English
Author keyword
CXCL 12 Chemokines Diabetes Inflammation Kidney Progression SDF
Keyword (fr)
Animal Chimiokine Diabète de type 2 Inflammation Modèle animal Podocyte Rein Souris Glomérulosclérose Appareil urinaire Endocrinopathie Maladie métabolique Mammalia Néphropathie glomérulaire Pathologie de l'appareil urinaire Pathologie du rein Rodentia Vertebrata
Keyword (en)
Animal Chemokine Type 2 diabetes Inflammation Animal model Podocyte Kidney Mouse Glomerulosclerosis Urinary system Endocrinopathy Metabolic diseases Mammalia Glomerulonephritis Urinary system disease Kidney disease Rodentia Vertebrata
Keyword (es)
Animal Quimioquina Diabetes de tipo 2 Inflamación Modelo animal Podocito Riñón Ratón Glomeruloesclerosis Aparato urinario Endocrinopatía Metabolismo patología Mammalia Nefropatía glomerular Aparato urinario patología Riñón patología Rodentia Vertebrata
Classification
Pascal
002 Biological and medical sciences / 002B Medical sciences / 002B14 Nephrology. Urinary tract diseases / 002B14A Nephropathies. Renovascular diseases. Renal failure / 002B14A01 Glomerulonephritis

Pascal
002 Biological and medical sciences / 002B Medical sciences / 002B21 Endocrinopathies / 002B21E Endocrine pancreas. Apud cells (diseases) / 002B21E01 Diabetes. Impaired glucose tolerance / 002B21E01A Etiopathogenesis. Screening. Investigations. Target tissue resistance

Discipline
Endocrinopathies Nephrology. Urinary tract diseases
Origin
Inist-CNRS
Database
PASCAL
INIST identifier
22024136

Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS

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