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2-Oxoglutarate analogue inhibitors of prolyl hydroxylase domain 2

Author
MECINOVIC, Jasmin1 ; LOENARZ, Christoph1 ; CHOWDHURY, Rasheduzzaman1 ; SCHOFIELD, Christopher J1
[1] Chemistry Research Laboratory, University of Oxford, 12 Mansfield Road, Oxford OX1 3TA, United Kingdom
Source

Bioorganic & medicinal chemistry letters (Print). 2009, Vol 19, Num 21, pp 6192-6195, 4 p ; ref : 28 ref

ISSN
0960-894X
Scientific domain
Biochemistry, molecular biology, biophysics; Pharmacology drugs
Publisher
Elsevier, Amsterdam
Publication country
Netherlands
Document type
Article
Language
English
Author keyword
2-Oxoglutarate Hypoxia Inhibition Mass spectrometry Prolyl hydroxylase domain 2
Keyword (fr)
Acide carboxylique Cétoacide Dicétone Electrospray Hypoxie In vitro Inhibiteur enzyme Inhibition Oxygène Procollagen-proline dioxygenase Relation structure activité Spectrométrie masse α-Aminoacide Glycine(N-alcoxyoxalyl) Heptanoïque acide(4,6-dioxo) Oxalique acide dérivé Propionique acide(3-hydroxycarbamoyl) Enzyme Oxidoreductases
Keyword (en)
Carboxylic acid Ketoacid Diketone Electrospray Hypoxia In vitro Enzyme inhibitor Inhibition Oxygen Procollagen-proline dioxygenase Structure activity relation Mass spectrometry α-Aminoacid Enzyme Oxidoreductases
Keyword (es)
Acido carboxílico Cetoácido Dicetona Electrospray Hipoxia In vitro Inhibidor enzima Inhibición Oxígeno Procollagen-proline dioxygenase Relación estructura actividad Espectrometría masa α-Aminoácido Enzima Oxidoreductases
Classification
Pascal
002 Biological and medical sciences / 002A Fundamental and applied biological sciences. Psychology / 002A02 Analytical, structural and metabolic biochemistry / 002A02E Enzymes and enzyme inhibitors / 002A02E02 Oxidoreductases

Pascal
002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02W Miscellaneous

Discipline
Analytical, structural and metabolic biochemistry General pharmacology
Origin
Inist-CNRS
Database
PASCAL
INIST identifier
22052691

Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS

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