Long-term effects of losartan on structure and function of the thoracic aorta in a mouse model of Marfan syndrome
- Author
- CLARICE YANG, H. H1 ; JONG MOO KIM1 ; CHUM, Elliott1 ; VAN BREEMEN, Cornelis1 ; CHUNG, Ada Wy1
[1] Department of Cardiovascular Science, Child and Family Research Institute, University of British Columbia, Vancouver, BC, Canada - Source
British journal of pharmacology. 2009, Vol 158, Num 6, pp 1503-1512, 10 p ; ref : 1 p.1/4
- CODEN
- BJPCBM
- ISSN
- 0007-1188
- Scientific domain
- Pharmacology drugs
- Publisher
- Nature Publishing Group, Basingstoke
- Publication country
- United Kingdom
- Document type
- Article
- Language
- English
- Author keyword
- Marfan syndrome aortic contractile function endothelial-dependent relaxation long-term treatment losartan thoracic aortic aneurysm
- Keyword (fr)
- Antihypertenseur Anévrysme aortique Aorte thoracique Endothélium Long terme Losartan Modèle animal Souris Syndrome de Marfan Traitement Récepteur AT1 de l'angiotensine II Angiotensine II Antagoniste angiotensine Appareil circulatoire Artère Composé non peptide Dérivé de l'imidazole Dérivé du biphényle Dérivé du tétrazole Hormone peptide Maladie de système Maladie héréditaire Mammalia Octapeptide Pathologie de l'appareil circulatoire Pathologie de la peau Pathologie du tissu conjonctif Pathologie du tissu élastique Rodentia Sartan dérivé Système renin angiotensine Vaisseau sanguin Vertebrata
- Keyword (en)
- Antihypertensive agent Aortic aneurysm Thoracic aorta Endothelium Long term Losartan Animal model Mouse Marfan syndrome Treatment Angiotensin II Angiotensin antagonist Circulatory system Artery Non peptide compound Imidazole derivatives Biphenyl derivatives Tetrazole derivatives Peptide hormone Systemic disease Genetic disease Mammalia Octapeptide Cardiovascular disease Skin disease Connective tissue disease Elastic tissue disease Rodentia Sartan derivatives Renin angiotensin system Blood vessel Vertebrata
- Keyword (es)
- Antihipertensivo Aneurisma de aorta Aorta torácica Endotelio Largo plazo Losartán Modelo animal Ratón Marfan síndrome Tratamiento Angiotensina II Antagonista angiotensina Aparato circulatorio Arteria Compuesto no péptido Imidazol derivado Bifenilo derivado Tetrazol derivado Hormona péptido Enfermedad sistémica Enfermedad hereditaria Mammalia Octapéptido Aparato circulatorio patología Piel patología Tejido conjuntivo patología Tejido elástico patología Rodentia Sartan derivado Sistema renin angiotensina Vaso sanguíneo Vertebrata
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B07 Sarcoidosis. Granulomatous diseases of unproved etiology. Connective tissue diseases. Elastic tissue diseases. Vasculitis
- Discipline
- General pharmacology Sarcoidosis. Granulomatosis of undetermined origin. Connective tissue diseases. Vasculitides
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 22102854
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1111/j.1476-5381.2009.00443.x 
https://dx.doi.org/10.1111/j.1476-5381.2009.00443.x
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