Isosorbide-Based Aspirin Prodrugs: Integration of Nitric Oxide Releasing Groups
- Autor
- JONES, Michael1 ; INKIELEWICZ, Iwona1 ; KHAN, Denise1 ; O'BYRNE, Paul1 ; HARMON, Shona1 ; HOLLAND, Valerie1 ; CLANCY, John M1 ; GILMER, John F1 ; MEDINA, Carlos1 ; SANTOS-MARTINEZ, Maria Jose1 ; RADOMSKI, Anna1 ; RADOMSKI, Marek W1 ; LALLY, Maeve N1 ; MORIARTY, Louise M1 ; GAYNOR, Joanne1 ; CAROLAN, Ciaran G1
[1] School of Pharmacy and Pharmaceutical Sciences, Trinity College, Dublin 2, Ireland - Fuente
Journal of medicinal chemistry (Print). 2009, Vol 52, Num 21, pp 6588-6598, 11 p ; ref : 35 ref
- CODEN
- JMCMAR
- ISSN
- 0022-2623
- Campo Científico
- Pharmacology drugs
- Editor
- American Chemical Society, Columbus, OH
- País de la publicación
- United States
- Tipo de documento
- Article
- Idioma
- English
- Palabra clave (fr)
- Acide acétylsalicylique Activité biologique Anticoagulant Cholinesterase Cinétique Ester Hydrolyse In vitro Inhibiteur thromboagrégation Isosorbide Liquide biologique Plasma sanguin Promédicament Sang Synthèse chimique Donneur azote monoxyde Carboxylic ester hydrolases Enzyme Esterases Hydrolases Salicylés
- Palabra clave (in)
- Acetylsalicylic acid Biological activity Anticoagulant Cholinesterase Kinetics Ester Hydrolysis In vitro Antiplatelet agent Isosorbide Biological fluid Blood plasma Prodrug Blood Chemical synthesis Nitric oxide donor Carboxylic ester hydrolases Enzyme Esterases Hydrolases Salicylates
- Palabra clave (es)
- Acetilsalicilico ácido Actividad biológica Anticoagulante Cholinesterase Cinética Ester Hidrólisis In vitro Inhibidor tromboagregación Isosorbida Líquido biológico Plasma sanguíneo Promedicamento Sangre Síntesis química Carboxylic ester hydrolases Enzima Esterases Hydrolases Salicilatos
- Clasificación
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02G Blood. Blood coagulation. Reticuloendothelial system
- Disciplina
- Pharmacological treatments
- Procedencia
- Inist-CNRS
- Base de datos
- PASCAL
- Identificador INIST
- 22108228
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1021/jm900561s 
https://dx.doi.org/10.1021/jm900561s
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