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Population Analysis of Myelosuppression Profiles Using Routine Clinical Data after the ICE (Ifosfamide/ Carboplatin/Etoposide) Regimen for Malignant Gliomas

Author
YANO, Yoshitaka1 ; KODAWARA, Takaaki2 ; HONGO, Haruyuki2 ; YANO, Ikuko2 ; KISHI, Y. O3 ; TAKAHASHI, Jun3 ; INUI, Ken-Ichi2
[1] Center for Integrative Education of Pharmacy Frontier, Graduate School of Pharmaceutical Sciences, Kyoto University, 46-29 Shimoadachi-cho, Yoshida, Sakyo-ku, Kyoto 606-8501, Japan
[2] Department of Pharmacy, Kyoto University Hospital, Faculty of Medicine, Kyoto University, 54 Kawahara-cho, Shogoin, Sakyo-ku, Kyoto 606-8507, Japan
[3] Department of Neurosurgery, Graduate School of Medicine, Kyoto University, 54 Kawahara-cho, Shogoin, Sakyo-ku, Kyoto 606-8507, Japan
Source

Journal of pharmaceutical sciences. 2009, Vol 98, Num 11, pp 4402-4412, 11 p ; ref : 32 ref

CODEN
JPMSAE
ISSN
0022-3549
Scientific domain
Pharmacology drugs
Publisher
American Pharmaceutical Association, Washington, DC / Wiley, Hoboken, NJ
Publication country
United States
Document type
Article
Language
English
Author keyword
ICE cancer chemotherapy erlang distribution modeling and simulation myelosuppresion pharmacodynamics population analysis
Keyword (fr)
Activité biologique Anticancéreux Carboplatine Chimiothérapie Distribution Etoposide Gliome malin Ifosfamide Modélisation Simulation Technologie pharmaceutique Tumeur maligne Agent alkylant Antimitotique Cancer DNA topoisomerase (ATP-hydrolysing) Dérivé de l'oxazaphosphinane Dérivé de la podophyllotoxine Enzyme Inhibiteur de la topoisomérase II Inhibiteur enzyme Isomerases Moutarde à l'azote Pathologie du système nerveux central Pathologie du système nerveux Pharmacocinétique Platine II Complexe Traitement
Keyword (en)
Biological activity Antineoplastic agent Carboplatin Chemotherapy Distribution Etoposide Malignant glioma Ifosfamide Modeling Simulation Pharmaceutical technology Malignant tumor Alkylating agent Antimitotic Cancer DNA topoisomerase (ATP-hydrolysing) Oxazaphosphinane derivatives Podophyllotoxin derivatives Enzyme Topoisomerase II inhibitor Enzyme inhibitor Isomerases Nitrogen mustard Central nervous system disease Nervous system diseases Pharmacokinetics Platinum II Complexes Treatment
Keyword (es)
Actividad biológica Anticanceroso Carboplatino Quimioterapia Distribución Etopósido Glioma maligno Ifosfamida Modelización Simulación Tecnología farmacéutica Tumor maligno Agente alquilante Antimitótico Cáncer DNA topoisomerase (ATP-hydrolysing) Oxazafosfinano derivado Podofilotoxina derivado Enzima Inhibidor topoisomerase II Inhibidor enzima Isomerases Mostaza al nitrógeno Sistema nervosio central patología Sistema nervioso patología Farmacocinética Platino II Complejo Tratamiento
Classification
Pascal
002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02A General pharmacology / 002B02A03 Pharmaceutical technology. Pharmaceutical industry

Discipline
General pharmacology
Origin
Inist-CNRS
Database
PASCAL
INIST identifier
22139613

Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS

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