Effect of Rifampin and Nelfinavir on the Metabolism of Methadone and Buprenorphine in Primary Cultures of Human Hepatocytes
- Author
- MOODY, David E1 ; FANG, Wenfang B1 ; LIN, Shen-Nan1 ; WEYANT, Denise M2 ; STROM, Stephen C3 ; OMIECINSKI, Curtis J2
[1] Center for Human Toxicology, Department of Pharmacology and Toxicology, University of Utah, Salt Lake City, Utah, United States
[2] Center for Molecular Toxicology and Carcinogenesis, Department of Veterinary and Biomedical Sciences, Pennsylvania State University, University Park, Pennsylvania, United States
[3] Department of Pathology, University of Pittsburgh, Pittsburgh, Pennsylvania, United States - Source
Drug metabolism and disposition. 2009, Vol 37, Num 12, pp 2323-2329, 7 p ; ref : 3/4 p
- CODEN
- DMDSAI
- ISSN
- 0090-9556
- Scientific domain
- Pharmacology drugs
- Publisher
- American Society for Pharmacology and Experimental Therapeutics, Bethesda, MD
- Publication country
- United States
- Document type
- Article
- Language
- English
- Keyword (fr)
- Analgésique narcotique Antibactérien Antibiotique Antirétroviral Antituberculeux Antiviral Buprénorphine Culture primaire Homme Hépatocyte In vitro Médicament Métabolisme Méthadone Nelfinavir Pharmacothérapie Rifampicine Appareil digestif Enzyme Foie Hydrolases Inhibiteur enzyme Inhibiteur protease Inhibiteur synthèse protéique Opiacés Peptidases Pharmacocinétique Traitement
- Keyword (en)
- Narcotic analgesic Antibacterial agent Antibiotic Antiretroviral agent Antituberculous agent Antiviral Buprenorphine Primary culture Human Hepatocyte In vitro Drug Metabolism Methadone Nelfinavir Pharmacotherapy Rifampicin Digestive system Enzyme Liver Hydrolases Enzyme inhibitor Protease inhibitor Protein synthesis inhibitor Opiates Peptidases Pharmacokinetics Treatment
- Keyword (es)
- Analgésico narcotico Antibacteriano Antibiótico Antiretroviral Antituberculoso Antiviral Buprenorfina Cultivo primario Hombre Hepatocito In vitro Medicamento Metabolismo Metadona Nelfinavir Farmacoterapia Rifampicina Aparato digestivo Enzima Hígado Hydrolases Inhibidor enzima Inhibidor proteasa Inhibidor síntesis proteica Opiados Peptidases Farmacocinética Tratamiento
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02A General pharmacology / 002B02A05 Pharmacokinetics. Pharmacogenetics. Drug-receptor interactions
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02S Antibiotics. Antiinfectious agents. Antiparasitic agents
- Discipline
- General pharmacology Pharmacological treatments
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 22162510
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1124/dmd.109.028605 
https://dx.doi.org/10.1124/dmd.109.028605
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