Pharmacokinetically Guided Dose Adjustment of 5-Fluorouracil: A Rational Approach to Improving Therapeutic Outcomes
- Author
- WASIF SAIF, M1 ; CHOMA, Adrienne2 ; SALAMONE, Salvatore J2 ; CHU, Edward1
[1] Developmental Therapeutics Program, Yale Cancer Center, Yale University School of Medicine, New Haven, CT, United States
[2] Saladax Biomedical Inc, Bethlehem, PA, United States - Source
Journal of the National Cancer Institute. 2009, Vol 101, Num 22, pp 1543-1552, 10 p ; ref : 71 ref
- ISSN
- 0027-8874
- Scientific domain
- Medical oncology
- Publisher
- Oxford University Press, Cary, NC
- Publication country
- United States
- Document type
- Article
- Language
- English
- Keyword (fr)
- Anticancéreux Cancérologie Chimiothérapie Fluorouracil Guide Homme Pharmacocinétique Posologie Traitement Tumeur maligne Antimétabolite Cancer Dérivé de la fluoropyrimidine Dérivé de la pyrimidine Enzyme Inhibiteur enzyme Methyltransferases Thymidylate synthase Transferases
- Keyword (en)
- Antineoplastic agent Cancerology Chemotherapy Fluorouracil Guide Human Pharmacokinetics Posology Treatment Malignant tumor Antimetabolic Cancer Fluoropyrimidine derivatives Pyrimidine derivatives Enzyme Enzyme inhibitor Methyltransferases Thymidylate synthase Transferases
- Keyword (es)
- Anticanceroso Cancerología Quimioterapia Fluorouracilo Guía Hombre Farmacocinética Posología Tratamiento Tumor maligno Antimetabólito Cáncer Fluoropirimidina derivado Pirimidina derivado Enzima Inhibidor enzima Methyltransferases Thymidylate synthase Transferases
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02R Antineoplastic agents / 002B02R02 Chemotherapy
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B04 Tumors / 002B04C Multiple tumors. Solid tumors. Tumors in childhood (general aspects)
- Discipline
- Pharmacological treatments Tumours
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 22174366
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1093/jnci/djp328 
https://dx.doi.org/10.1093/jnci/djp328
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