1-(2-Aminoethyl)-3-(arylsulfonyl)-1H-pyrrolopyridines are 5-HT6 receptor ligands
- Author
- BERNOTAS, Ronald C1 ; ANTANE, Schuyler A2 ; LENICEK, Steven E2 ; HAYDAR, Simon N2 ; ROBICHAUD, Albert J2 ; HARRISON, Boyd L2 ; GUO MING ZHANG3 ; SMITH, Deborah3 ; COUPET, Joseph3 ; SCHECHTER, Lee E3
[1] Chemical Sciences, Wyeth Research, 500 Arcola Road, Collegeville, PA 19426, United States
[2] Chemical Sciences, Wyeth Research, CN 8000, Princeton, NJ 08543, United States
[3] Neuroscience, Wyeth Research, CN 8000, Princeton, NJ 08543, United States - Source
Bioorganic & medicinal chemistry letters (Print). 2009, Vol 19, Num 24, pp 6935-6938, 4 p
- ISSN
- 0960-894X
- Scientific domain
- Biochemistry, molecular biology, biophysics; Pharmacology drugs
- Publisher
- Elsevier, Amsterdam
- Publication country
- Netherlands
- Document type
- Article
- Language
- English
- Author keyword
- 5-HT6 receptor Agonist Antagonist Pyrrolo[2,3-c]pyridine Pyrrolo[3,2-b]pyridine Pyrrolo[3,2-c]pyridine Serotonin Sulfone
- Keyword (fr)
- Affinité Agoniste Amine tertiaire Antagoniste Composé bicyclique Hétérocycle azote In vitro Isomère position Relation structure activité Récepteur sérotoninergique 5-HT6 Sulfone Synthèse chimique Sérotonine Pyrrolo[2,3-c]pyridine dérivé Pyrrolo[3,2-b]pyridine dérivé Pyrrolo[3,2-c]pyridine dérivé Pyrrolopyridine
- Keyword (en)
- Affinity Agonist Tertiary amine Antagonist Bicyclic compound Nitrogen heterocycle In vitro Position isomer Structure activity relation 5-HT6 serotonin receptor Sulfone Chemical synthesis Serotonin
- Keyword (es)
- Afinidad Agonista Amina terciaria Antagonista Compuesto bicíclico Heterociclo nitrógeno In vitro Isómero posición Relación estructura actividad Receptor serotoninérgico 5-HT6 Sulfona Síntesis química Serotonina
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02B Neuropharmacology / 002B02B09 Neurotransmitters. Neurotransmission. Receptors / 002B02B09C Serotoninergic system
- Discipline
- Pharmacological treatments
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 22176553
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1016/j.bmcl.2009.10.067 
https://dx.doi.org/10.1016/j.bmcl.2009.10.067
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