Single-Cell Expression Profiling of Dopaminergic Neurons Combined with Association Analysis Identifies Pyridoxal Kinase as Parkinson's Disease Gene
- Author
- ELSTNER, Matthias1 2 ; MORRIS, Christopher M3 ; GIOVANETTI, Alessandro8 ; ZEVIANI, Massimo8 ; BURN, David J6 ; MCKEITH, Ian G6 ; PERRY, Robert H6 ; JAROS, E6 ; KRÜGER, Rejko4 ; WICHMANN, H.-Erich9 ; SCHREIBER, Stefan10 ; CAMPBELL, Harry11 ; HEIM, Katharina1 ; WILSON, James F12 ; WRIGHT, Alan F13 ; DUNLOP, Malcolm14 ; PISTIS, Giorgio15 ; TONIOLO, Daniela15 16 ; CHINNERY, Patrick F5 6 ; GASSER, Thomas4 ; KLOPSTOCK, Thomas2 ; MEITINGER, Thomas1 17 ; PROKISCH, Holger1 17 ; LICHTNER, Peter1 ; TURNBULL, Douglass M5 ; BENDER, Andreas2 ; MEHTA, Divya1 ; SCHULTE, Claudia4 ; SHARMA, Manu4 ; HUDSON, Gavin5 6 ; GOLDWURM, Stefano7
[1] Institute of Human Genetics, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany
[2] Department of Neurology, Ludwig-Maximilians-University, Munich, Germany
[3] Medical Toxicology Centre, Wolfson Unit of Clinical Pharmacology, Newcastle University, Newcastle upon Tyne, United Kingdom
[4] Section for Neurodegenerative Diseases, Hertie-Institute for Clinical Brain Research, University of Tübingen, Tübingen, Germany
[5] Mitochondrial Research Group, Institute for Ageing and Health, Newcastle University, Newcastle upon Tyne, United Kingdom
[6] Institute for Ageing and Health, Newcastle University, Newcastle upon Tyne, United Kingdom
[7] Parkinson Institute, Istituti Clinici di Perfezionamento, Milan, Italy
[8] Unit of Molecular Neurogenetics, IRCCS Foundation Neurological Institute C. Besta, Milan, Italy
[9] Institute of Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany
[10] Institute of Clinical Molecular Biology, Christian-Albrechts University, Kiel, Germany
[11] Community Health Sciences and Institute for Genetics and Molecular Medicine, University of Edinburgh Medical School, Edinburgh, United Kingdom
[12] Centre for Population Health Sciences, University of Edinburgh, Edinburgh, United Kingdom
[13] Institute of Genetics and Molecular Medicine, MRC Human Genetics Unit, Edinburgh, United Kingdom
[14] Institute of Genetics and Molecular Medicine, Colon Cancer Genetics Group, University of Edinburgh and MRC Human Genetics Unit, Edinburgh, United Kingdom
[15] San Raffaele Scientific Institute, Division of Genetics and Cell Biology, Milan, Italy
[16] Istituto di Genetica Molecolare -Consiglio Nazionale delle Ricerche, Pavia, Italy
[17] Institute of Human Genetics, Technical University Munich, Munich, Germany - Source
Annals of neurology. 2009, Vol 66, Num 6, pp 792-798, 7 p ; ref : 27 ref
- Publisher
- Wiley-Liss, Hoboken, NJ
- Publication country
- United States
- Document type
- Article
- Language
- English
- Keyword (fr)
- Maladie de Parkinson Neurone dopaminergique Pathologie du système nerveux Pyridoxal kinase Enzyme Maladie dégénérative Pathologie de l'encéphale Pathologie du système nerveux central Syndrome extrapyramidal Transferases
- Keyword (en)
- Parkinson disease Dopaminergic neuron Nervous system diseases Pyridoxal kinase Enzyme Degenerative disease Cerebral disorder Central nervous system disease Extrapyramidal syndrome Transferases
- Keyword (es)
- Parkinson enfermedad Neurona dopaminérgica Sistema nervioso patología Pyridoxal kinase Enzima Enfermedad degenerativa Encéfalo patología Sistema nervosio central patología Extrapiramidal síndrome Transferases
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B17 Neurology / 002B17G Degenerative and inherited degenerative diseases of the nervous system. Leukodystrophies. Prion diseases
- Discipline
- Neurology
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 22272507
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1002/ana.21780 
https://dx.doi.org/10.1002/ana.21780
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