A small-cell lung cancer genome with complex signatures of tobacco exposure
- Author
- PLEASANCE, Erin D1 ; STEPHENS, Philip J1 ; VARELA, Ignacio1 ; NIK-ZAINAL, Serena1 ; DAVIES, Helen R1 ; ORDONEZ, Gonzalo R1 ; MUDIE, Laura J1 ; LATIMER, Calli1 ; EDKINS, Sarah1 ; STEBBINGS, Lucy1 ; CHEN, Lina1 ; MINGMING JIA1 ; O'MEARA, Sarah1 2 ; LEROY, Catherine1 ; MARSHALL, John; MENZIES, Andrew; BUTLER, Adam; TEAGUE, Jon W; MANGION, Jonathon2 ; SUN, Yongming A4 ; MCLAUGHLIN, Stephen F5 ; PECKHAM, Heather E5 ; TSUNG, Eric F5 ; MCBRIDE, David J1 ; COSTA, Gina L5 ; LEE, Clarence C5 ; MINNA, John D6 ; GAZDAR, Adi6 ; BIRNEY, Ewan3 ; RHODES, Michael D4 ; MCKERNAN, Kevin J5 ; STRATTON, Michael R7 ; FUTREAL, P. Andrew; CAMPBELL, Peter J8 ; MEYNERT, Alison3 ; JONES, David1 ; LIN, Meng-Lay1 ; BEARE, David1 ; KING WAI LAU1 ; GREENMAN, Chris1
[1] Wellcome Trust Sanger Institute, Hinxton CB10 1SA, United Kingdom
[2] Life Technologies, Warrington WA3 7QH, United Kingdom
[3] European Bioinformatics Institute, Hinxton CB10 1SD, United Kingdom
[4] Life Technologies, Foster City, California 94404, United States
[5] Life Technologies, Beverley, Massachusetts 01915, United States
[6] University of Texas Southwestern Medical Center, Dallas, Texas 75390, United States
[7] Institute of Cancer Research, Sutton, Surrey SM2 5NG, United Kingdom
[8] Department of Haematology, University of Cambridge, CB2 2XY, United Kingdom - Source
Nature (London). 2010, Vol 463, Num 7278, pp 184-190, 7 p ; ref : 40 ref
- CODEN
- NATUAS
- ISSN
- 0028-0836
- Scientific domain
- Multidisciplinary
- Publisher
- Nature Publishing Group, London
- Publication country
- United Kingdom
- Document type
- Article
- Language
- English
- Keyword (fr)
- Carcinogène Exposition Fumée tabac Génome Lignée cellulaire Mutation somatique Pathologie des poumons Substitution Séquençage Tabagisme Tumeur maligne Gène de fusion Cancer
- Keyword (en)
- Carcinogen Exposure Tobacco smoke Genome Cell line Somatic mutation Lung disease Substitution Sequencing Tobacco smoking Malignant tumor Fusion gene Cancer
- Keyword (es)
- Carcinógeno Exposición Humo tabaco Genoma Línea celular Mutación somática Pulmón patología Substitución Sequencing Tabaquismo Tumor maligno Cáncer
- Classification
- Pascal
- 002 Biological and medical sciences / 002A Fundamental and applied biological sciences. Psychology / 002A04 Molecular and cellular biology / 002A04H Cell physiology / 002A04H04 Cell transformation and carcinogenesis. Action of oncogenes and antioncogenes
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B03 Toxicology / 002B03E Tobacco, tobacco smoking
- Discipline
- Molecular and cell biology Toxicology
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 22292891
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1038/nature08629 
https://dx.doi.org/10.1038/nature08629
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arXiv access
