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Surface-engineered targeted PPI dendrimer for efficient intracellular and intratumoral siRNA delivery

Author
TARATULA, Oleh1 2 ; GARBUZENKO, Olga B1 ; KIRKPATRICK, Paul2 ; PANDYA, Ipsit2 ; SAVLA, Ronak1 2 ; POZHAROV, Vitaly P1 ; HUIXIN HE2 ; MINKO, Tamara1
[1] Department of Pharmaceutics, Rutgers, The State University of New Jersey, Piscataway, NJ 08854, United States
[2] Department of Chemistry, Rutgers, The State University of New Jersey, Newark, NJ 07102, United States
Conference title
Drug carriers: progress beyond delivery
Conference name
International Symposium on Recent Advances in Drug Delivery Systems (14 ; Salt Lake City, UT 2009-02-15)
Author (monograph)
HENNINK, Wim E (Editor)1
[1] Department of Pharmaceutics, University of Utrecht, Netherlands
Source

Journal of controlled release. 2009, Vol 140, Num 3, pp 284-293, 10 p ; ref : 40 ref

CODEN
JCREEC
ISSN
0168-3659
Scientific domain
Pharmacology drugs
Publisher
Elsevier, Kidlington
Publication country
United Kingdom
Document type
Conference Paper
Language
English
Author keyword
Cytotoxicity In vivo imaging LHRH peptide Poly(propyleneimine) dendrimer Tumor targeting siRNA targeted to BCL2 mRNA
Keyword (fr)
ARNsi Ciblage Cible Cytotoxicité Gonadotrophine RH Imagerie médicale In vivo Interférence ARN Peptide RNA messager Silence expression génique Structure dendritique Technologie pharmaceutique Tumeur maligne Voie intratumorale Dendrimère Cancer Polymère ramifié
Keyword (en)
siRNA Targeting Target Cytotoxicity Gonadotropin RH Medical imagery In vivo RNA interference Peptides Messenger RNA Gene silencing Dendritic structure Pharmaceutical technology Malignant tumor Intratumoral administration Dendrimer Cancer Branched polymer
Keyword (es)
ARNsi Blancado Blanco Citotoxicidad Gonadotropina RH Imaginería médica In vivo ARN interferencia Péptido RNA mensajero Silencio expresión genética Estructura dendrítica Tecnología farmacéutica Tumor maligno Vía intratumoral Dendrímero Cáncer Polímero ramificado
Classification
Pascal
002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02A General pharmacology / 002B02A03 Pharmaceutical technology. Pharmaceutical industry

Discipline
General pharmacology
Origin
Inist-CNRS
Database
PASCAL
INIST identifier
22323950

Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS

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