A new highly penetrant form of obesity due to deletions on chromosome 16p11.2
- Author
- WALTERS, R. G1 2 ; JACQUEMONT, S3 ; DELOBEL, B10 ; STUTZMANN, F9 ; EL-SAYED MOUSTAFA, J. S1 ; CHEVRE, J.-C9 ; LECOEUR, C9 ; VATIN, V9 ; BOUQUILLON, S8 ; BUXTON, J. L1 ; BOUTE, O11 ; HOLDER-ESPINASSE, M11 ; VALSESIA, A4 5 6 ; CUISSET, J.-M12 ; LEMAITRE, M.-P12 ; AMBRESIN, A.-E13 ; BRIOSCHI, A14 ; GAILLARD, M3 ; GIUSTI, V15 ; FELLMANN, F3 ; FERRARINI, A3 ; HADJIKHANI, N16 7 ; CAMPION, D17 ; DE SMITH, A. J1 ; GUILMATRE, A17 ; GOLDENBERG, A18 ; CALMELS, N19 ; MANDEL, J.-L19 ; LE CAIGNEC, C20 21 ; DAVID, A20 ; ISIDOR, B20 ; CORDIER, M.-P22 ; DUPUIS-GIROD, S22 ; LABALME, A22 ; MARTINET, D3 ; SANLAVILLE, D22 23 ; BERI-DEXHEIMER, M24 ; JONVEAUX, P24 ; LEHEUP, B24 25 ; OUNAP, K; BOCHUKOVA, E. G; HENNING, E; KEOGH, J; ELLIS, R. J; MACDERMOT, K. D; ANDERSSON, J1 ; VAN HAELST, M. M; VINCENT-DELORME, C; PLESSIS, G; TOURAINE, R; FALCHI, M1 ; CHEN, F7 ; ANDRIEUX, J8 ; LOBBENS, S9
[1] Section of Genomic Medicine, Imperial College London, London W12 0NN, United Kingdom
[2] Department of Epidemiology and Public Health, Imperial College London, London W2 1PG, United Kingdom
[3] Service de Génétique Médicale, Centre Hospitalier Universitaire Vaudois, 1011 Lausanne, Switzerland
[4] Departement de Génétique Médicale, Université de Lausanne, 1015 Lausanne, Switzerland
[5] Ludwig Institute for Cancer Research, Université de Lausanne, 1015 Lausanne, Switzerland
[6] Swiss Institute of Bioinformatics, 1015 Lausanne, Switzerland
[7] Brain Mind Institute, École Polytechnique Fédérale de Lausanne, 1015 Lausanne, Switzerland
[8] Laboratoire de Génétique Médicale, Centre Hospitalier Regional Universitaire, 59000 Lille, France
[9] CNRS 8090-Institute of Biology, Pasteur Institute, 59800 Lille, France
[10] Centre de Génétique Chromosomique, Hôpital Saint-Vincent de Paul, GHICL, 59020 Lille, France
[11] Service de Génétique Clinique, Hôpital Jeanne de Flandre, Centre Hospitalier Universitaire de Lille, 59000 Lille, France
[12] Service de Neuropédiatrie, Centre Hospitalier Regional Universitaire, 59000 Lille, France
[13] Unité Multidisciplinaire de Santé des Adolescents, Centre Hospitalier Universitaire Vaudois, 1011 Lausanne, Switzerland
[14] Service de Neuropsychologie et de Neuroréhabilitation, Centre Hospitalier Universitaire Vaudois, 1011 Lausanne, Switzerland
[15] Service d'Endocrinologie, Centre Hospitalier Universitaire Vaudois, 1011 Lausanne, Switzerland
[16] Athinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Harvard Medical School, Charlestown, Massachusetts 02129, United States
[17] INSERM, U614, Faculté de Médecine, 76183 Rouen, France
[18] Service de Génétique, Centre Hospitalier Universitaire de Rouen, 76031 Rouen, France
[19] Laboratoire de Diagnostic Génétique, Nouvel Hôpital civil, 67091 Strasbourg, France
[20] Centre Hospitalier Universitaire Nantes, Service de Génétique Médicale, 44093 Nantes, France
[21] INSERT, UMR915, L'Institut du Thorax, 44007 Nantes, France
[22] Service de Génétique, Hospices Civils de Lyon, Hôpital de l'Hotel Dieu, 69288 Lyon, France
[23] EA 4171, Université Claude Bernard, 69622 Lyon, France
[24] Laboratoire de Génétique, Centre Hospitalier Universitaire, Nancy Université, 54511 Vandoeuvre les Nancy, France
[25] EA4368 Medical School Nancy, Université Henri Poincaré, 54003 Nancy, France - Source
Nature (London). 2010, Vol 463, Num 7281, pp 671-675, 5 p ; ref : 30 ref
- CODEN
- NATUAS
- ISSN
- 0028-0836
- Scientific domain
- Multidisciplinary
- Publisher
- Nature Publishing Group, London
- Publication country
- United Kingdom
- Document type
- Article
- Language
- English
- Keyword (fr)
- Chromosome Délétion Etat nutritionnel Obésité Trouble de la nutrition
- Keyword (en)
- Chromosome Deletion Nutritional status Obesity Nutrition disorder
- Keyword (es)
- Cromosoma Deleción Estado nutricional Obesidad Trastorno nutricíon
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B22 Metabolic diseases / 002B22B Obesity
- Discipline
- Metabolic diseases
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 22355565
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1038/nature08727 
https://dx.doi.org/10.1038/nature08727
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arXiv access
