Potent transglutaminase inhibitors, aryl β-aminoethyl ketones
- Author
- OZAKI, Shoichiro1 ; EBISUI, Etsuko1 ; HAMADA, Kozo1 2 ; GOTO, Jun-Ichi1 ; SUZUKI, Akinobu Z1 ; TERAUCHI, Akiko1 2 ; MIKOSHIBA, Katsuhiko1 2
[1] Laboratory for Developmental Neurobiology, Brain Science Institute, Institute of Physical and Chemical Research (RIKEN), 2-1 Hirosawa, Wako, Saitama 351-0198, Japan
[2] Calcium Oscillation Project, ICORP-SORST, Japan Science and Technology Agency (JST), 4-1-8 Honcho, Kawaguchi, Saitama 332-0012, Japan - Source
Bioorganic & medicinal chemistry letters (Print). 2010, Vol 20, Num 3, pp 1141-1144, 4 p
- ISSN
- 0960-894X
- Scientific domain
- Biochemistry, molecular biology, biophysics; Pharmacology drugs
- Publisher
- Elsevier, Amsterdam
- Publication country
- Netherlands
- Document type
- Article
- Language
- English
- Author keyword
- Alzheimer's disease Celiac disease Huntington's disease Parkinson's disease Protein cross-link inhibitor Transglutaminase inhibitor
- Keyword (fr)
- Activité biologique Aminocétone Brome Composé organique Chorée de Huntington Cétone Démence d'Alzheimer Dérivé du thiophène In vitro Inhibiteur Maladie coeliaque Maladie de Parkinson Protein-glutamine γ-glutamyltransferase Protéine Réticulation Synthèse chimique Propan-1-one(3-[benzyl t-butyl amino]-1-[5-bromo-2-thiényl]) Acyltransferases Aminoacyltransferases Enzyme Immunopathologie Malabsorption intestinale Maladie dégénérative Maladie héréditaire Pathologie de l'appareil digestif Pathologie de l'encéphale Pathologie de l'intestin Pathologie du système nerveux central Pathologie du système nerveux Syndrome extrapyramidal Transferases
- Keyword (en)
- Biological activity Aminoketone Bromine Organic compounds Huntington disease Ketone Alzheimer disease Thiophene derivatives In vitro Inhibitor Coeliac disease Parkinson disease Protein-glutamine γ-glutamyltransferase Protein Crosslinking Chemical synthesis Acyltransferases Aminoacyltransferases Enzyme Immunopathology Intestinal malabsorption Degenerative disease Genetic disease Digestive diseases Cerebral disorder Intestinal disease Central nervous system disease Nervous system diseases Extrapyramidal syndrome Transferases
- Keyword (es)
- Actividad biológica Aminocetona Bromo Compuesto orgánico Corea Huntington Cetona Demencia Alzheimer Tiofeno derivado In vitro Inhibidor Enfermedad celíaca Parkinson enfermedad Protein-glutamine γ-glutamyltransferase Proteína Reticulación Síntesis química Acyltransferases Aminoacyltransferases Enzima Inmunopatología Malabsorción intestinal Enfermedad degenerativa Enfermedad hereditaria Aparato digestivo patología Encéfalo patología Intestino patología Sistema nervosio central patología Sistema nervioso patología Extrapiramidal síndrome Transferases
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02B Neuropharmacology / 002B02B02 Psychoanaleptics: cns stimulant, antidepressant agent, nootropic agent, mood stabilizer..., (alzheimer disease)
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02H Digestive system
- Francis
- 770 Psychology. Psychoanalysis. Psychiatry / 770-E Psychopharmacology / 770-E02 Psychoanaleptics: cns stimulant, antidepressant agent, nootropic agent, mood stabilizer…
- Discipline
- Pharmacological treatments Psychopathology. Psychiatry. Clinical psychology
- Origin
- Inist-CNRS
- Database
- FRANCIS ; PASCAL
- INIST identifier
- 22363183
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1016/j.bmcl.2009.12.011 
https://dx.doi.org/10.1016/j.bmcl.2009.12.011
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