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Up-regulation of the type 3 ryanodine receptor is neuroprotective in the TgCRND8 mouse model of Alzheimer's disease

Author
SUPNET, Charlene1 2 ; NOONAN, Charmaine3 ; RICHARD, Kelly4 ; BRADLEY, John5 ; MAYNE, Michael1 2
[1] Department of Biomedical Sciences, University of Prince Edward Island, Charlottetown, PE, Canada
[2] Institute for Nutrisciences and Health, National Research Council of Canada, Charlottetown, PE, Canada
[3] MRSB Consulting Services, Charlottetown, PE, Canada
[4] Atlantic Centre for Comparative Biomedical Research, Atlantic Veterinary College, Charlottetown, PE, Canada
[5] Millennium Pharmaceuticals, Cambridge, Massachusetts, United States
Source

Journal of neurochemistry. 2010, Vol 112, Num 2, pp 356-365, 10 p ; ref : 1 p

CODEN
JONRA9
ISSN
0022-3042
Scientific domain
Cell biology, histology; Neurology; Physiology, morphology
Publisher
Wiley-Blackwell, Oxford
Publication country
United Kingdom
Document type
Article
Language
English
Author keyword
Alzheimer's disease TgCRND8 endoplasmic reticulum intracellular calcium neuroprotection ryanodine receptor
Keyword (fr)
Calcium Démence d'Alzheimer Intracellulaire Libération Modèle animal Mort cellulaire Neurone Potassium Protéine Ryanodine Récepteur ryanodine RY3 Récepteur ryanodine Souris Stress Maladie dégénérative Mammalia Pathologie de l'encéphale Pathologie du système nerveux central Pathologie du système nerveux Rodentia Vertebrata
Keyword (en)
Calcium Alzheimer disease Intracellular Release Animal model Cell death Neuron Potassium Protein Ryanodine Ryanodine receptor RY3 Ryanodine receptor Mouse Stress Degenerative disease Mammalia Cerebral disorder Central nervous system disease Nervous system diseases Rodentia Vertebrata
Keyword (es)
Calcio Demencia Alzheimer Intracelular Liberación Modelo animal Muerte celular Neurona Potasio Proteína Ryanodina Receptor ryanodina RY3 Receptor ryanodina Ratón Estrés Enfermedad degenerativa Mammalia Encéfalo patología Sistema nervosio central patología Sistema nervioso patología Rodentia Vertebrata
Classification
Pascal
002 Biological and medical sciences / 002B Medical sciences / 002B17 Neurology / 002B17G Degenerative and inherited degenerative diseases of the nervous system. Leukodystrophies. Prion diseases

Pascal
002 Biological and medical sciences / 002B Medical sciences / 002B18 Psychopathology. Psychiatry / 002B18C Adult and adolescent clinical studies / 002B18C13 Organic mental disorders. Neuropsychology

Francis
770 Psychology. Psychoanalysis. Psychiatry / 770-D Psychopathology. Psychiatry / 770-D03 Adult and adolescent clinical studies / 770-D03M Organic mental disorders. Neuropsychology

Discipline
Neurology Psychopathology. Psychiatry. Clinical psychology
Origin
Inist-CNRS
Database
FRANCIS ; PASCAL
INIST identifier
22368548

Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS

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