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Novel hybrids from lamellarin D and combretastatin A 4 as cytotoxic agents

Author
LI SHEN1 ; XIAOCHUN YANG2 ; BO YANG2 ; QIAOJUN HE2 ; YONGZHOU HU1
[1] ZJU-ENS Joint Laboratory of Medicinal Chemistry, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310058, China
[2] Institute of Pharmacology and Toxicology, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310058, China
Source

European journal of medicinal chemistry. 2010, Vol 45, Num 1, pp 11-18, 8 p ; ref : 25 ref

CODEN
EJMCA5
ISSN
0223-5234
Scientific domain
Organic chemistry; Pharmacology drugs
Publisher
Elsevier, Kidlington
Publication country
United Kingdom
Document type
Article
Language
English
Author keyword
Anti-proliferative Combretastatin A 4 Cytotoxic Hybrids Lamellarin D
Keyword (fr)
Anticancéreux Antimitotique Antitubuline Carcinome hépatocellulaire Cellule tumorale Cytotoxicité Côlon Estomac Homme In vitro Leucémie Lignée cellulaire Poumon Relation structure activité Synthèse chimique Tumeur solide Combretastatine A4 dérivé Lamellarine dérivé Lignée A549 Lignée HCT116 Lignée K562 Lignée SGC7901 Lignée SMMC7721 Pyrrolo[2,1-a]isoquinoléine dérivé Pyrrolo[2,1-a]isoquinoléine(1,2-diaryl-4,5-dihydro-8,9-diméthoxy) Pyrroloisoquinoléine
Keyword (en)
Antineoplastic agent Antimitotic Antitubulin Hepatocellular carcinoma Tumor cell Cytotoxicity Colon Stomach Human In vitro Leukemia Cell line Lung Structure activity relation Chemical synthesis Solid tumor
Keyword (es)
Anticanceroso Antimitótico Antitubulina Carcinoma hepatocelular Célula tumoral Citotoxicidad Colón Estómago Hombre In vitro Leucemia Línea celular Pulmón Relación estructura actividad Síntesis química Tumor sólido
Classification
Pascal
002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02R Antineoplastic agents / 002B02R01 General aspects

Discipline
Pharmacological treatments
Origin
Inist-CNRS
Database
PASCAL
INIST identifier
22375568

Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS

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