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SA4503, a sigma-1 receptor agonist, prevents cultured cortical neurons from oxidative stress-induced cell death via suppression of MAPK pathway activation and glutamate receptor expression

Author
TUERXUN, Tuerhong1 2 ; NUMAKAWA, Tadahiro1 2 3 ; ADACHI, Naoki2 3 ; KUMAMARU, Emi2 ; KITAZAWA, Hiromi1 2 ; KUDO, Motoshige1 ; KUNUGI, Hiroshi2 3
[1] Department of Pathology, Tokyo Medical University, Tokyo, 160-8401, Japan
[2] Department of Mental Disorder Research, National Institute of Neuroscience, National Center of Neurology and Psychiatry, Tokyo, 187-8502, Japan
[3] Core Research for Evolutional Science and Technology Program (CREST), Japan Science and Technology Agency (JST), Saitama, 332-0012, Japan
Source

Neuroscience letters. 2010, Vol 469, Num 3, pp 303-308, 6 p ; ref : 32 ref

CODEN
NELED5
ISSN
0304-3940
Scientific domain
Neurology; Physiology, morphology
Publisher
Elsevier, Shannon
Publication country
Ireland
Document type
Article
Language
English
Author keyword
AMPA Antidepressant Cell death ERK MAPK SA4503
Keyword (fr)
Agoniste Antidépresseur Extracellular signal-regulated protein kinase In vitro Mitogen-activated protein kinase Mort cellulaire Récepteur glutamate Stress oxydatif Récepteur sigma 1 Enzyme Transferases
Keyword (en)
Agonist Antidepressant agent Extracellular signal-regulated protein kinase In vitro Mitogen-activated protein kinase Cell death Glutamate receptor Oxidative stress Sigma 1 receptor Enzyme Transferases
Keyword (es)
Agonista Antidepresor Extracellular signal-regulated protein kinase In vitro Mitogen-activated protein kinase Muerte celular Receptor glutámato Estrés oxidativo Receptor sigma 1 Enzima Transferases
Classification
Pascal
002 Biological and medical sciences / 002A Fundamental and applied biological sciences. Psychology / 002A25 Vertebrates: nervous system and sense organs

Pascal
002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02B Neuropharmacology / 002B02B02 Psychoanaleptics: cns stimulant, antidepressant agent, nootropic agent, mood stabilizer..., (alzheimer disease)

Francis
770 Psychology. Psychoanalysis. Psychiatry / 770-E Psychopharmacology / 770-E02 Psychoanaleptics: cns stimulant, antidepressant agent, nootropic agent, mood stabilizer…

Discipline
Pharmacological treatments Psychopathology. Psychiatry. Clinical psychology Vertebrates : nervous system and sense organs
Origin
Inist-CNRS
Database
FRANCIS ; PASCAL
INIST identifier
22464742

Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS

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