Prediction of acetylcholinesterase inhibitors and characterization of correlative molecular descriptors by machine learning methods
- Author
- WEI LV1 ; YING XUE1 2
[1] Key Laboratory of Green Chemistry and Technology in Ministry of Education, College of Chemistry, Sichuan University, Chengdu 610064, China
[2] State Key Laboratory of Biotherapy, Sichuan University, Chengdu 610041, China - Source
European journal of medicinal chemistry. 2010, Vol 45, Num 3, pp 1167-1172, 6 p ; ref : 67 ref
- CODEN
- EJMCA5
- ISSN
- 0223-5234
- Scientific domain
- Organic chemistry; Pharmacology drugs
- Publisher
- Elsevier, Kidlington
- Publication country
- United Kingdom
- Document type
- Article
- Language
- English
- Author keyword
- Acetylcholinesterase (AChE) Alzheimer's disease (AD) Machine learning methods (ML methods) Molecular descriptors Recursive feature elimination (RFE) Support vector machine (SVM)
- Keyword (fr)
- Acetylcholinesterase Antialzheimer Anticholinestérasique Apprentissage(intelligence artificielle) Inhibiteur enzyme Machine vecteur support Modèle moléculaire Modélisation Prédiction Inhibiteur acetylcholinesterase Carboxylic ester hydrolases Enzyme Esterases Hydrolases
- Keyword (en)
- Acetylcholinesterase Antialzheimer agent Anticholinesterase agent Learning (artificial intelligence) Enzyme inhibitor Support vector machine Molecular model Modeling Prediction Carboxylic ester hydrolases Enzyme Esterases Hydrolases
- Keyword (es)
- Acetylcholinesterase Antialzheimer Anticolinesterasa agente Inhibidor enzima Máquina vector soporte Modelo molecular Modelización Predicción Carboxylic ester hydrolases Enzima Esterases Hydrolases
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02B Neuropharmacology / 002B02B02 Psychoanaleptics: cns stimulant, antidepressant agent, nootropic agent, mood stabilizer..., (alzheimer disease)
- Francis
- 770 Psychology. Psychoanalysis. Psychiatry / 770-E Psychopharmacology / 770-E02 Psychoanaleptics: cns stimulant, antidepressant agent, nootropic agent, mood stabilizer…
- Discipline
- Pharmacological treatments Psychopathology. Psychiatry. Clinical psychology
- Origin
- Inist-CNRS
- Database
- FRANCIS ; PASCAL
- INIST identifier
- 22468570
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1016/j.ejmech.2009.12.038 
https://dx.doi.org/10.1016/j.ejmech.2009.12.038
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