Cocoa flavonoids up-regulate antioxidant enzyme activity via the ERK1/2 pathway to protect against oxidative stress-induced apoptosis in HepG2 cells
- Author
- MARTIN, Maria Angeles1 ; GRANADO SERRANO, Ana Belén1 ; RAMOS, Sonia1 ; IZQUIERDO PULIDO, Maria2 ; BRAVO, Laura1 ; GOYA, Luis1
[1] Department of Metabolism and Nutrition, Instituto de Ciencia y Ternología de los Alimentos y Nutrición (formerly Instituto del Frío), CSIC, Ciudad Universitaria, 28040 Madrid, Spain
[2] Department of Nutrition and Food Science, Facultad de Farmacia, Universidad de Barcelona, 28028 Barcelona, Spain - Source
Journal of nutritional biochemistry. 2010, Vol 21, Num 3, pp 196-205, 10 p ; ref : 48 ref
- ISSN
- 0955-2863
- Scientific domain
- Nutrition, obesity, metabolic disorders
- Publisher
- Elsevier, New York, NY
- Publication country
- United States
- Document type
- Article
- Language
- English
- Author keyword
- Apoptosis Glutathione peroxidase Glutathione reductase Polyphenols ROS Signaling pathways
- Keyword (fr)
- Activité enzymatique Antioxydant Apoptose Cacao Flavonoïde Glutathion Glutathione peroxidase Mammalia Polyphénol Régulation Stress oxydatif Transduction signal Enzyme Oxidoreductases Peroxidases Vertebrata
- Keyword (en)
- Enzymatic activity Antioxidant Apoptosis Cocoa Flavonoid Glutathione Glutathione peroxidase Mammalia Polyphenol Regulation(control) Oxidative stress Signal transduction Enzyme Oxidoreductases Peroxidases Vertebrata
- Keyword (es)
- Actividad enzimática Antioxidante Apoptosis Cacao Flavonoide Glutatión Glutathione peroxidase Mammalia Polifenol Regulación Estrés oxidativo Transducción señal Enzima Oxidoreductases Peroxidases Vertebrata
- Classification
- Pascal
- 002 Biological and medical sciences / 002A Fundamental and applied biological sciences. Psychology / 002A16 Vertebrates: anatomy and physiology, studies on body, several organs or systems / 002A16E Feeding. Feeding behavior
- Discipline
- Vertebrates : anatomy and physiology, studies on body, several organs or systems
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 22486226
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1016/j.jnutbio.2008.10.009 
https://dx.doi.org/10.1016/j.jnutbio.2008.10.009
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