Skp2 targeting suppresses tumorigenesis by Arf-p53-independent cellular senescence
- Author
- LIN, Hui-Kuan1 2 3 ; ZHENBANG CHEN1 2 4 ; CORDON-CARDO, Carlos2 ; TERUYA-FELDSTEIN, Julie2 ; PAOLO PANDOLFI, Pier1 2 4 ; GUOCAN WANG1 2 4 ; NARDELLA, Caterina1 2 4 ; LEE, Szu-Wei3 ; CHAN, Chan-Hsin3 ; YANG, Wei-Lei3 ; JING WANG3 ; EGIA, Ainara4 ; NAKAYAMA, Keiichi I5
[1] Cancer Biology and Genetics Program, Memorial Sloan-Kettering Cancer Center, 1275 York Avenue, New York, New York 10021, United States
[2] Department of Pathology, Sloan-Kettering Institute, Memorial Sloan-Kettering Cancer Center, 1275 York Avenue, New York, New York 10021, United States
[3] Department of Molecular and Cellular Oncology, The University of Texas M.D. Anderson Cancer Center, Houston, Texas 77030, United States
[4] Cancer Genetics Program, Beth Israel Deaconess Cancer Center and Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, 330 Brookline Avenue, Boston, Massachusetts 02215, United States
[5] Department of Molecular and Cellular Biology, Medical Institute of Bioregulation, Kyushu University, Fukuoka, Fukuoka 812-8582, Japan - Source
Nature (London). 2010, Vol 464, Num 7287, pp 374-379, 6 p ; ref : 41 ref
- CODEN
- NATUAS
- ISSN
- 0028-0836
- Scientific domain
- Multidisciplinary
- Publisher
- Nature Publishing Group, London
- Publication country
- United Kingdom
- Document type
- Article
- Language
- English
- Keyword (fr)
- Animal Cancérologie Carcinogenèse Gène TP53 Gène suppresseur tumeur Souris Suppression Sénescence Tumeur maligne Tumorigénicité Gène ARF Gène SKP2 Cancer Génétique Mammalia Rodentia Vertebrata
- Keyword (en)
- Animal Cancerology Carcinogenesis TP53 Gene Tumor suppressor gene Mouse Suppression Senescence Malignant tumor Tumorigenicity Cancer Genetics Mammalia Rodentia Vertebrata
- Keyword (es)
- Animal Cancerología Carcinogénesis Gen TP53 Gen supresor tumor Ratón Supresión Senescencia Tumor maligno Tumorigenicidad Cáncer Genética Mammalia Rodentia Vertebrata
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B04 Tumors / 002B04E Carcinogenesis, carcinogens and anticarcinogens / 002B04E01 General aspects
- Discipline
- Tumours
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 22500713
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1038/nature08815 
https://dx.doi.org/10.1038/nature08815
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