Induction of apoptosis by thymoquinone in lymphoblastic leukemia Jurkat cells is mediated by a p73-dependent pathway which targets the epigenetic integrator UHRF1
- Author
- ALHOSIN, Mahmoud1 ; ABUSNINA, Abdurazzag1 ; FUHRMANN, Guy1 ; ACHOUR, Mayada1 ; SHARIF, Tanveer1 ; MULLER, Christian2 ; PELUSO, Jean2 ; CHATAIGNEAU, Thierry1 ; LUGNIER, Claire1 ; SCHINI-KERTH, Valérie B1 ; BRONNER, Christian1
[1] CNRS UMR 7213 Laboratoire de Biophotonique et Pharmacologie, Faculté de Pharmacie, 74 route du Rhin, 67401 Illkirch, France
[2] CNRS UMR 7200 Laboratoire d'Innovation Thérapeutique, Université de Strasbourg, Faculté de Pharmacie, 74 route du Rhin, 67401 Illkirch, France - Source
Biochemical pharmacology. 2010, Vol 79, Num 9, pp 1251-1260, 10 p ; ref : 40 ref
- CODEN
- BCPCA6
- ISSN
- 0006-2952
- Scientific domain
- Biochemistry, molecular biology, biophysics; Pharmacology drugs; Physiology, morphology
- Publisher
- Elsevier, Amsterdam
- Publication country
- Netherlands
- Document type
- Article
- Language
- English
- Author keyword
- Apoptosis Caspase Thymoquinone Tumor suppressor protein p73 UHRF1
- Keyword (fr)
- Apoptose Caspase Cellule tumorale Ciblage Cible Cysteine endopeptidases Epigénétique Gène suppresseur tumeur Induction Leucémie aiguë lymphoblastique Mort cellulaire Gène p73 Hémopathie maligne lymphoïde Lignée Jurkat Protéine p73 Cancer Enzyme Hydrolases Hémopathie maligne Peptidases Syndrome lymphoprolifératif
- Keyword (en)
- Apoptosis Caspase Tumor cell Targeting Target Cysteine endopeptidases Epigenetics Tumor suppressor gene Induction Acute lymphocytic leukemia Cell death Lymphoid neoplasm Cancer Enzyme Hydrolases Malignant hemopathy Peptidases Lymphoproliferative syndrome
- Keyword (es)
- Apoptosis Caspase Célula tumoral Blancado Blanco Cysteine endopeptidases Epigenética Gen supresor tumor Inducción Leucemia aguda linfoblástica Muerte celular Cáncer Enzima Hydrolases Hemopatía maligna Peptidases Linfoproliferativo síndrome
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B19 Hematologic and hematopoietic diseases / 002B19B Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis
- Discipline
- Blood diseases General pharmacology
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 22545070
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1016/j.bcp.2009.12.015 
https://dx.doi.org/10.1016/j.bcp.2009.12.015
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