2-Methoxyestradiol induces endoreduplication through the induction of mitochondrial oxidative stress and the activation of MAPK signaling pathways
- Author
- TING, C. M1 ; LEE, Y. M1 ; WONG, C. K. C1 ; WONG, A. S2 ; LUNG, H. L3 ; LUNG, M. L3 ; LO, K. W4 ; WONG, R. N. S1 ; MAK, N. K1
[1] Department of Biology, Hong Kong Baptist University, 224, Waterloo Road, Hong-Kong
[2] School of Biological Sciences, University of Hong Kong, Hong-Kong
[3] Department of Clinical Oncology, University of Hong Kong, Hong-Kong
[4] Department of Anatomical and Cellular Pathology and State Key Laboratory in Oncology in South China, The Chinese University of Hong Kong, Hong-Kong - Source
Biochemical pharmacology. 2010, Vol 79, Num 6, pp 825-841, 17 p ; ref : 42 ref
- CODEN
- BCPCA6
- ISSN
- 0006-2952
- Scientific domain
- Biochemistry, molecular biology, biophysics; Pharmacology drugs; Physiology, morphology
- Publisher
- Elsevier, Amsterdam
- Publication country
- Netherlands
- Document type
- Article
- Language
- English
- Author keyword
- 2-Methoxyestradiol Endoreduplication MAPK signaling pathways Mitochondria Nasopharyngeal carcinoma Oxidative stress
- Keyword (fr)
- Anticancéreux Cancer du nasopharynx Carcinome du nasopharynx Endomitose Induction Mitochondrie Mitogen-activated protein kinase Stress oxydatif Transduction signal Estradiol(2-méthoxy) Voie de signalisation Cancer Enzyme Pathologie ORL Pathologie du pharynx Transferases Tumeur maligne
- Keyword (en)
- Antineoplastic agent Nasopharynx cancer Nasopharynx carcinoma Endomitosis Induction Mitochondria Mitogen-activated protein kinase Oxidative stress Signal transduction Signaling pathway Cancer Enzyme ENT disease Pharynx disease Transferases Malignant tumor
- Keyword (es)
- Anticanceroso Cáncer del nasopharynx Carcinoma nasofaringe Endomitosis Inducción Mitocondria Mitogen-activated protein kinase Estrés oxidativo Transducción señal Cáncer Enzima ORL patología Faringe patología Transferases Tumor maligno
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B10 Otorhinolaryngology. Stomatology / 002B10B Upper respiratory tract, upper alimentary tract, paranasal sinuses, salivary glands: diseases, semeiology / 002B10B01 Tumors
- Discipline
- General pharmacology Otorhinolaryngology. Stomatology
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 22561620
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1016/j.bcp.2009.10.018 
https://dx.doi.org/10.1016/j.bcp.2009.10.018
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