CRTAP deficiency leads to abnormally high bone matrix mineralization in a murine model and in children with osteogenesis imperfecta type VII
- Author
- FRATZL-ZELMAN, N1 ; MORELLO, R2 ; LEE, B2 3 ; RAUCH, F4 ; GLORIEUX, F. H4 ; MISOF, B. M1 ; KLAUSHOFER, K1 ; ROSCHGER, P1
[1] Ludwig Boltzmann Institute of Osteology at Hanusch Hospital of WGKK and AUVA Trauma Centre Meidling, 4th Med. Department Hanusch Hospital, Vienna, Austria
[2] Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX, United States
[3] Howard Hughes Medical Institute, Houston, TX, United States
[4] Genetics Unit, Shriners Hospital for Children, Montreal, Canada - Source
Bone (New York, NY). 2010, Vol 46, Num 3, pp 820-826, 7 p ; ref : 40 ref
- ISSN
- 8756-3282
- Scientific domain
- Orthopedics traumatology; Physiology, morphology
- Publisher
- Elsevier, Amsterdam
- Publication country
- Netherlands
- Document type
- Article
- Language
- English
- Author keyword
- (qBEI) Bone biopsy Bone mineralization CRTAP deficiency Mouse femur Quantitative backscattered electron imaging density distribution (BMDD)
- Keyword (fr)
- Analyse quantitative Animal Biopsie Densité Déficit Enfant Fémur Matrice osseuse Minéralisation Modèle Morphologie Os Ostéogenèse imparfaite Souris Homme Maladie héréditaire Mammalia Ostéochondrodysplasie Pathologie du système ostéoarticulaire Rodentia Vertebrata
- Keyword (en)
- Quantitative analysis Animal Biopsy Density Deficiency Child Femur Bone matrix Mineralization Models Morphology Bone Osteogenesis imperfecta Mouse Human Genetic disease Mammalia Osteochondrodysplasia Diseases of the osteoarticular system Rodentia Vertebrata
- Keyword (es)
- Análisis cuantitativo Animal Biopsia Densidad Déficiencia Niño Fémur Matriz ósea Mineralización Modelo Morfología Hueso Osteogénesis imperfecta Ratón Hombre Enfermedad hereditaria Mammalia Osteocondrodisplasia Sistema osteoarticular patología Rodentia Vertebrata
- Classification
- Pascal
- 002 Biological and medical sciences / 002A Fundamental and applied biological sciences. Psychology / 002A04 Molecular and cellular biology / 002A04H Cell physiology / 002A04H15 Mineralization, calcification
- Pascal
- 002 Biological and medical sciences / 002A Fundamental and applied biological sciences. Psychology / 002A16 Vertebrates: anatomy and physiology, studies on body, several organs or systems
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B15 Diseases of the osteoarticular system / 002B15H Malformations and congenital and or hereditary diseases involving bones. Joint deformations
- Discipline
- Molecular and cell biology Osteoarticular pathology Vertebrates : anatomy and physiology, studies on body, several organs or systems
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 22592890
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1016/j.bone.2009.10.037 
https://dx.doi.org/10.1016/j.bone.2009.10.037
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