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Integrative analytical approach by capillary electrophoresis and kinetics under high pressure optimized for deciphering intrinsic and extrinsic cofactors that modulate activity and stability of human paraoxonase (PON1)

Author
RENAULT, Frédérique1 ; CARUS, Tiffany1 ; CLERY-BARRAUD, Cécile1 ; ELIAS, Mikael2 ; CHABRIERE, Eric2 ; MASSON, Patrick1 ; ROCHU, Daniel1
[1] Département de Toxicologie, Institut de Recherche Biomédicale des Armées, Antenne La Tronche-CRSSA, BP 87, 38702 La Tronche, France
[2] Architecture et Fonction des Macromolécules Biologiques, CNRS-Université de la Méditerranée, 13288 Marseille, France
Conference title
BIOANALYSIS OF ORGANOPHOSPHORUS TOXICANTS AND CORRESPONDING ANTIDOTES: Including Selected Papers from the 12th Medical Chemical Defence Conference, 22-23 April 2009, Munich, Germany
Conference name
MCDC (Medical Chemical Defence Conference) (Medical Chemical Defence Conference) (12 ; Munich 2009-04-22)
Author (monograph)
JOHN, Harald (Editor)1 ; THIERMANN, Horst (Editor)1
[1] Bundeswehr Institute of Pharmacology and Toxicology, Neuherbergstr. 11, 80937 Munich, Germany
Source

Journal of chromatography. B. 2010, Vol 878, Num 17-18, pp 1346-1355, 10 p ; ref : 43 ref

ISSN
1570-0232
Scientific domain
Medical laboratory techniques; Pharmacology drugs
Publisher
Elsevier, Amsterdam
Publication country
Netherlands
Document type
Conference Paper
Language
English
Author keyword
Capillary electrophoresis Functional stability High hydrostatic pressure Human phosphate binding protein Oligomerization Paraoxonase
Keyword (fr)
Aryldialkylphosphatase Cinétique Effet pression Electrophorèse capillaire Homme Oligomérisation Optimisation Phosphate Pression hydrostatique Protéine liaison Stabilité Enzyme Esterases Hydrolases Phosphoric triester hydrolases Propriété physicochimique
Keyword (en)
Aryldialkylphosphatase Kinetics Pressure effect Capillary electrophoresis Human Oligomerization Optimization Phosphates Hydrostatic pressure Binding protein Stability Enzyme Esterases Hydrolases Phosphoric triester hydrolases Physicochemical properties
Keyword (es)
Aryldialkylphosphatase Cinética Efecto presión Electroforesis capilar Hombre Oligomerización Optimización Fosfato Presión hidrostática Proteína enlace Estabilidad Enzima Esterases Hydrolases Phosphoric triester hydrolases Propiedad fisicoquímica
Classification
Pascal
002 Biological and medical sciences / 002A Fundamental and applied biological sciences. Psychology / 002A02 Analytical, structural and metabolic biochemistry

Pascal
002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02A General pharmacology / 002B02A02 Analysis

Discipline
Analytical, structural and metabolic biochemistry General pharmacology
Origin
Inist-CNRS
Database
PASCAL
INIST identifier
22758869

Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS

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