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15-Deoxy-Δ12,14-prostaglandin J2 stabilizes, but functionally inactivates p53 by binding to the cysteine 277 residue

Author
KIM, D.-H1 ; KIM, E.-H1 ; NA, H.-K2 ; SUN, Y3 ; SURH, Y.-J1 4 5
[1] College of Pharmacy, Seoul National University, Seoul, Korea, Republic of
[2] Department of Food and Nutrition, Sungshin Women's University, Seoul, Korea, Republic of
[3] Department of Radiation Oncology, University of Michigan Comprehensive Cancer Center, Ann Arbor, MI, United States
[4] Department of Molecular Medicine and Biopharmaceutical Sciences, Graduate School of Convergence Science and Technology, Seoul National University, Seoul, Korea, Republic of
[5] Cancer Research Institute, Seoul National University, Seoul, Korea, Republic of
Source

Oncogene (Basingstoke). 2010, Vol 29, Num 17, pp 2560-2576, 17 p ; ref : 2 p

ISSN
0950-9232
Scientific domain
Cell biology, histology; Medical oncology; Genetics
Publisher
Nature Publishing Group, Basingstoke
Publication country
United Kingdom
Document type
Article
Language
English
Author keyword
15-deoxy-Δ12,14-prostaglandin J2 cyclopentenone prostaglandin p53 thiol modification
Keyword (fr)
Carcinogenèse Cystéine Gène TP53 Gène suppresseur tumeur Prostaglandine Thiol Dérivé de l'acide arachidonique Eicosanoïde
Keyword (en)
Carcinogenesis Cysteine TP53 Gene Tumor suppressor gene Prostaglandin Thiol Arachidonic acid derivatives Eicosanoid
Keyword (es)
Carcinogénesis Cisteína Gen TP53 Gen supresor tumor Prostaglandina Tiol Araquidónico ácido derivado Eicosanoide
Classification
Pascal
002 Biological and medical sciences / 002A Fundamental and applied biological sciences. Psychology / 002A04 Molecular and cellular biology / 002A04H Cell physiology / 002A04H04 Cell transformation and carcinogenesis. Action of oncogenes and antioncogenes

Discipline
Molecular and cell biology
Origin
Inist-CNRS
Database
PASCAL
INIST identifier
22770604

Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS

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