Explaining variability in ciclosporin exposure in adult kidney transplant recipients
- Author
- PRESS, Rogier R2 ; PLOEGER, Bart A4 5 ; DEN HARTIGH, Jan1 ; VAN DER STRAATEN, T1 ; VAN PELT, Hans3 ; DANHOF, Meindert4 5 ; DE FIJTER, Hans2 ; GUCHELAAR, Henk-Jan1
[1] Department of Clinical Pharmacy and Toxicology, Leiden University Medical Center, Albinusdreef 2, 2333 ZA Leiden, Netherlands
[2] Department of Nephrology, Leiden University Medical Center, Albinusdreef 2, 2333 ZA Leiden, Netherlands
[3] Department of Clinical Chemistry, Leiden University Medical Center, Albinusdreef 2, 2333 ZA Leiden, Netherlands
[4] Leiden Amsterdam Center for Drug Research (LACDR), Einsteinweg 55, 2333 CC Leiden, Netherlands
[5] Leiden Experts on Advanced Pharmacokinetics and Pharmacodynamics (LAP&P Consultants BV), Archimedesweg 31, 2333 CM Leiden, Netherlands - Source
European journal of clinical pharmacology. 2010, Vol 66, Num 6, pp 579-590, 12 p ; ref : 46 ref
- ISSN
- 0031-6970
- Scientific domain
- Pharmacology drugs
- Publisher
- Springer, Heidelberg
- Publication country
- Germany
- Document type
- Article
- Language
- English
- Author keyword
- Ciclosporin A Pharmacogenetics Population pharmacokinetics Therapeutic drug monitoring
- Keyword (fr)
- Adulte Ciclosporine Exposition Immunodépresseur Pharmacocinétique de la population Pharmacogénétique Receveur Rein Suivi thérapeutique pharmacologique Traitement Transplantation Variabilité Appareil urinaire Chirurgie Greffe Génétique Homme Inhibiteur de la calcineurine
- Keyword (en)
- Adult Ciclosporin Exposure Immunosuppressive agent Population pharmacokinetics Pharmacogenetics Recipient Kidney Therapeutic drug monitoring Treatment Transplantation Variability Urinary system Surgery Graft Genetics Human Calcineurin inhibitor
- Keyword (es)
- Adulto Ciclosporina Exposición Inmunodepresor Farmacocinética población Farmacogenética Receptor Riñón Monitorización farmacoterapéutica Tratamiento Trasplantación Variabilidad Aparato urinario Cirugía Injerto Genética Hombre Inhibidor calcineurina
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments
- Discipline
- General pharmacology
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 22812363
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
Access to the document
Install on your browser
DOI
10.1007/s00228-010-0810-9 
https://dx.doi.org/10.1007/s00228-010-0810-9
"O:13:\"PanistOpenUrl\":36:{s:10:\"\u0000*\u0000openUrl\";N;s:6:\"\u0000*\u0000idc\";N;s:6:\"\u0000*\u0000fmt\";s:7:\"journal\";s:6:\"\u0000*\u0000doi\";s:25:\"10.1007\/s00228-010-0810-9\";s:6:\"\u0000*\u0000pii\";s:0:\"\";s:7:\"\u0000*\u0000pmid\";s:0:\"\";s:9:\"\u0000*\u0000atitle\";s:84:\"Explaining variability in ciclosporin exposure in adult kidney transplant recipients\";s:9:\"\u0000*\u0000jtitle\";s:41:\"European journal of clinical pharmacology\";s:9:\"\u0000*\u0000stitle\";s:23:\"Eur. j. clin. pharmacol\";s:7:\"\u0000*\u0000date\";s:4:\"2010\";s:9:\"\u0000*\u0000volume\";s:2:\"66\";s:8:\"\u0000*\u0000issue\";s:1:\"6\";s:8:\"\u0000*\u0000spage\";s:3:\"579\";s:8:\"\u0000*\u0000epage\";s:3:\"590\";s:8:\"\u0000*\u0000pages\";s:0:\"\";s:7:\"\u0000*\u0000issn\";s:9:\"0031-6970\";s:8:\"\u0000*\u0000eissn\";s:0:\"\";s:9:\"\u0000*\u0000aulast\";s:5:\"PRESS\";s:10:\"\u0000*\u0000aufirst\";s:8:\"Rogier R\";s:9:\"\u0000*\u0000auinit\";s:0:\"\";s:10:\"\u0000*\u0000auinitm\";s:0:\"\";s:5:\"\u0000*\u0000au\";a:7:{i:0;s:15:\"PLOEGER, Bart A\";i:1;s:16:\"DEN HARTIGH, Jan\";i:2;s:19:\"VAN DER STRAATEN, T\";i:3;s:14:\"VAN PELT, Hans\";i:4;s:16:\"DANHOF, Meindert\";i:5;s:15:\"DE FIJTER, Hans\";i:6;s:19:\"GUCHELAAR, Henk-Jan\";}s:9:\"\u0000*\u0000aucorp\";s:0:\"\";s:7:\"\u0000*\u0000isbn\";s:0:\"\";s:8:\"\u0000*\u0000coden\";s:0:\"\";s:8:\"\u0000*\u0000genre\";s:7:\"article\";s:7:\"\u0000*\u0000part\";s:0:\"\";s:9:\"\u0000*\u0000btitle\";s:0:\"\";s:8:\"\u0000*\u0000title\";s:84:\"Explaining variability in ciclosporin exposure in adult kidney transplant recipients\";s:8:\"\u0000*\u0000place\";s:10:\"Heidelberg\";s:6:\"\u0000*\u0000pub\";s:8:\"Springer\";s:10:\"\u0000*\u0000edition\";s:0:\"\";s:9:\"\u0000*\u0000tpages\";s:2:\"12\";s:9:\"\u0000*\u0000series\";s:0:\"\";s:8:\"\u0000*\u0000proxy\";s:30:\"http:\/\/proxyout.inist.fr:8080\/\";s:12:\"\u0000*\u0000integrite\";b:1;}"
Panist access
"O:12:\"IstexOpenUrl\":35:{s:10:\"\u0000*\u0000openUrl\";N;s:6:\"\u0000*\u0000fmt\";s:7:\"journal\";s:6:\"\u0000*\u0000doi\";s:25:\"10.1007\/s00228-010-0810-9\";s:6:\"\u0000*\u0000pii\";s:0:\"\";s:7:\"\u0000*\u0000pmid\";s:0:\"\";s:9:\"\u0000*\u0000atitle\";s:84:\"Explaining variability in ciclosporin exposure in adult kidney transplant recipients\";s:9:\"\u0000*\u0000jtitle\";s:41:\"European journal of clinical pharmacology\";s:9:\"\u0000*\u0000stitle\";s:23:\"Eur. j. clin. pharmacol\";s:7:\"\u0000*\u0000date\";s:4:\"2010\";s:9:\"\u0000*\u0000volume\";s:2:\"66\";s:8:\"\u0000*\u0000issue\";s:1:\"6\";s:8:\"\u0000*\u0000spage\";s:3:\"579\";s:8:\"\u0000*\u0000epage\";s:3:\"590\";s:8:\"\u0000*\u0000pages\";s:0:\"\";s:7:\"\u0000*\u0000issn\";s:9:\"0031-6970\";s:8:\"\u0000*\u0000eissn\";s:0:\"\";s:9:\"\u0000*\u0000aulast\";s:5:\"PRESS\";s:10:\"\u0000*\u0000aufirst\";s:8:\"Rogier R\";s:9:\"\u0000*\u0000auinit\";s:0:\"\";s:10:\"\u0000*\u0000auinitm\";s:0:\"\";s:5:\"\u0000*\u0000au\";a:7:{i:0;s:15:\"PLOEGER, Bart A\";i:1;s:16:\"DEN HARTIGH, Jan\";i:2;s:19:\"VAN DER STRAATEN, T\";i:3;s:14:\"VAN PELT, Hans\";i:4;s:16:\"DANHOF, Meindert\";i:5;s:15:\"DE FIJTER, Hans\";i:6;s:19:\"GUCHELAAR, Henk-Jan\";}s:9:\"\u0000*\u0000aucorp\";s:0:\"\";s:7:\"\u0000*\u0000isbn\";s:0:\"\";s:8:\"\u0000*\u0000coden\";s:0:\"\";s:8:\"\u0000*\u0000genre\";s:7:\"article\";s:7:\"\u0000*\u0000part\";s:0:\"\";s:9:\"\u0000*\u0000btitle\";s:0:\"\";s:8:\"\u0000*\u0000title\";s:84:\"Explaining variability in ciclosporin exposure in adult kidney transplant recipients\";s:8:\"\u0000*\u0000place\";s:10:\"Heidelberg\";s:6:\"\u0000*\u0000pub\";s:8:\"Springer\";s:10:\"\u0000*\u0000edition\";s:0:\"\";s:9:\"\u0000*\u0000tpages\";s:2:\"12\";s:9:\"\u0000*\u0000series\";s:0:\"\";s:8:\"\u0000*\u0000proxy\";s:30:\"http:\/\/proxyout.inist.fr:8080\/\";s:12:\"\u0000*\u0000integrite\";b:1;}"
Istex access
"O:16:\"UnpaywallOpenUrl\":35:{s:8:\"\u0000*\u0000email\";s:27:\"assistance-portail@inist.fr\";s:6:\"\u0000*\u0000fmt\";N;s:6:\"\u0000*\u0000doi\";s:25:\"10.1007\/s00228-010-0810-9\";s:6:\"\u0000*\u0000pii\";N;s:7:\"\u0000*\u0000pmid\";N;s:9:\"\u0000*\u0000atitle\";N;s:9:\"\u0000*\u0000jtitle\";N;s:9:\"\u0000*\u0000stitle\";N;s:7:\"\u0000*\u0000date\";N;s:9:\"\u0000*\u0000volume\";N;s:8:\"\u0000*\u0000issue\";N;s:8:\"\u0000*\u0000spage\";N;s:8:\"\u0000*\u0000epage\";N;s:8:\"\u0000*\u0000pages\";N;s:7:\"\u0000*\u0000issn\";N;s:8:\"\u0000*\u0000eissn\";N;s:9:\"\u0000*\u0000aulast\";N;s:10:\"\u0000*\u0000aufirst\";N;s:9:\"\u0000*\u0000auinit\";N;s:10:\"\u0000*\u0000auinitm\";N;s:5:\"\u0000*\u0000au\";N;s:9:\"\u0000*\u0000aucorp\";N;s:7:\"\u0000*\u0000isbn\";N;s:8:\"\u0000*\u0000coden\";N;s:8:\"\u0000*\u0000genre\";N;s:7:\"\u0000*\u0000part\";N;s:9:\"\u0000*\u0000btitle\";N;s:8:\"\u0000*\u0000title\";N;s:8:\"\u0000*\u0000place\";N;s:6:\"\u0000*\u0000pub\";N;s:10:\"\u0000*\u0000edition\";N;s:9:\"\u0000*\u0000tpages\";N;s:9:\"\u0000*\u0000series\";N;s:8:\"\u0000*\u0000proxy\";s:30:\"http:\/\/proxyout.inist.fr:8080\/\";s:12:\"\u0000*\u0000integrite\";N;}"
Unpaywall access
"O:16:\"EuropePMCOpenUrl\":35:{s:10:\"\u0000*\u0000openUrl\";N;s:6:\"\u0000*\u0000fmt\";s:7:\"journal\";s:6:\"\u0000*\u0000doi\";s:25:\"10.1007\/s00228-010-0810-9\";s:6:\"\u0000*\u0000pii\";s:0:\"\";s:7:\"\u0000*\u0000pmid\";s:0:\"\";s:9:\"\u0000*\u0000atitle\";s:84:\"Explaining variability in ciclosporin exposure in adult kidney transplant recipients\";s:9:\"\u0000*\u0000jtitle\";s:41:\"European journal of clinical pharmacology\";s:9:\"\u0000*\u0000stitle\";s:23:\"Eur. j. clin. pharmacol\";s:7:\"\u0000*\u0000date\";s:4:\"2010\";s:9:\"\u0000*\u0000volume\";s:2:\"66\";s:8:\"\u0000*\u0000issue\";s:1:\"6\";s:8:\"\u0000*\u0000spage\";s:3:\"579\";s:8:\"\u0000*\u0000epage\";s:3:\"590\";s:8:\"\u0000*\u0000pages\";s:0:\"\";s:7:\"\u0000*\u0000issn\";s:9:\"0031-6970\";s:8:\"\u0000*\u0000eissn\";s:0:\"\";s:9:\"\u0000*\u0000aulast\";s:5:\"PRESS\";s:10:\"\u0000*\u0000aufirst\";s:8:\"Rogier R\";s:9:\"\u0000*\u0000auinit\";s:0:\"\";s:10:\"\u0000*\u0000auinitm\";s:0:\"\";s:5:\"\u0000*\u0000au\";a:7:{i:0;s:15:\"PLOEGER, Bart A\";i:1;s:16:\"DEN HARTIGH, Jan\";i:2;s:19:\"VAN DER STRAATEN, T\";i:3;s:14:\"VAN PELT, Hans\";i:4;s:16:\"DANHOF, Meindert\";i:5;s:15:\"DE FIJTER, Hans\";i:6;s:19:\"GUCHELAAR, Henk-Jan\";}s:9:\"\u0000*\u0000aucorp\";s:0:\"\";s:7:\"\u0000*\u0000isbn\";s:0:\"\";s:8:\"\u0000*\u0000coden\";s:0:\"\";s:8:\"\u0000*\u0000genre\";s:7:\"article\";s:7:\"\u0000*\u0000part\";s:0:\"\";s:9:\"\u0000*\u0000btitle\";s:0:\"\";s:8:\"\u0000*\u0000title\";s:84:\"Explaining variability in ciclosporin exposure in adult kidney transplant recipients\";s:8:\"\u0000*\u0000place\";s:10:\"Heidelberg\";s:6:\"\u0000*\u0000pub\";s:8:\"Springer\";s:10:\"\u0000*\u0000edition\";s:0:\"\";s:9:\"\u0000*\u0000tpages\";s:2:\"12\";s:9:\"\u0000*\u0000series\";s:0:\"\";s:8:\"\u0000*\u0000proxy\";s:30:\"http:\/\/proxyout.inist.fr:8080\/\";s:12:\"\u0000*\u0000integrite\";b:1;}"
Europe PubMed Central access
"O:11:\"BaseOpenUrl\":35:{s:10:\"\u0000*\u0000openUrl\";N;s:6:\"\u0000*\u0000fmt\";s:7:\"journal\";s:6:\"\u0000*\u0000doi\";s:25:\"10.1007\/s00228-010-0810-9\";s:6:\"\u0000*\u0000pii\";s:0:\"\";s:7:\"\u0000*\u0000pmid\";s:0:\"\";s:9:\"\u0000*\u0000atitle\";s:84:\"Explaining variability in ciclosporin exposure in adult kidney transplant recipients\";s:9:\"\u0000*\u0000jtitle\";s:41:\"European journal of clinical pharmacology\";s:9:\"\u0000*\u0000stitle\";s:23:\"Eur. j. clin. pharmacol\";s:7:\"\u0000*\u0000date\";s:4:\"2010\";s:9:\"\u0000*\u0000volume\";s:2:\"66\";s:8:\"\u0000*\u0000issue\";s:1:\"6\";s:8:\"\u0000*\u0000spage\";s:3:\"579\";s:8:\"\u0000*\u0000epage\";s:3:\"590\";s:8:\"\u0000*\u0000pages\";s:0:\"\";s:7:\"\u0000*\u0000issn\";s:9:\"0031-6970\";s:8:\"\u0000*\u0000eissn\";s:0:\"\";s:9:\"\u0000*\u0000aulast\";s:5:\"PRESS\";s:10:\"\u0000*\u0000aufirst\";s:8:\"Rogier R\";s:9:\"\u0000*\u0000auinit\";s:0:\"\";s:10:\"\u0000*\u0000auinitm\";s:0:\"\";s:5:\"\u0000*\u0000au\";a:7:{i:0;s:15:\"PLOEGER, Bart A\";i:1;s:16:\"DEN HARTIGH, Jan\";i:2;s:19:\"VAN DER STRAATEN, T\";i:3;s:14:\"VAN PELT, Hans\";i:4;s:16:\"DANHOF, Meindert\";i:5;s:15:\"DE FIJTER, Hans\";i:6;s:19:\"GUCHELAAR, Henk-Jan\";}s:9:\"\u0000*\u0000aucorp\";s:0:\"\";s:7:\"\u0000*\u0000isbn\";s:0:\"\";s:8:\"\u0000*\u0000coden\";s:0:\"\";s:8:\"\u0000*\u0000genre\";s:7:\"article\";s:7:\"\u0000*\u0000part\";s:0:\"\";s:9:\"\u0000*\u0000btitle\";s:0:\"\";s:8:\"\u0000*\u0000title\";s:84:\"Explaining variability in ciclosporin exposure in adult kidney transplant recipients\";s:8:\"\u0000*\u0000place\";s:10:\"Heidelberg\";s:6:\"\u0000*\u0000pub\";s:8:\"Springer\";s:10:\"\u0000*\u0000edition\";s:0:\"\";s:9:\"\u0000*\u0000tpages\";s:2:\"12\";s:9:\"\u0000*\u0000series\";s:0:\"\";s:8:\"\u0000*\u0000proxy\";s:30:\"http:\/\/proxyout.inist.fr:8080\/\";s:12:\"\u0000*\u0000integrite\";b:1;}"
Base Search access
"O:12:\"ArXivOpenUrl\":35:{s:10:\"\u0000*\u0000openUrl\";N;s:6:\"\u0000*\u0000fmt\";s:7:\"journal\";s:6:\"\u0000*\u0000doi\";s:25:\"10.1007\/s00228-010-0810-9\";s:6:\"\u0000*\u0000pii\";s:0:\"\";s:7:\"\u0000*\u0000pmid\";s:0:\"\";s:9:\"\u0000*\u0000atitle\";s:84:\"Explaining variability in ciclosporin exposure in adult kidney transplant recipients\";s:9:\"\u0000*\u0000jtitle\";s:41:\"European journal of clinical pharmacology\";s:9:\"\u0000*\u0000stitle\";s:23:\"Eur. j. clin. pharmacol\";s:7:\"\u0000*\u0000date\";s:4:\"2010\";s:9:\"\u0000*\u0000volume\";s:2:\"66\";s:8:\"\u0000*\u0000issue\";s:1:\"6\";s:8:\"\u0000*\u0000spage\";s:3:\"579\";s:8:\"\u0000*\u0000epage\";s:3:\"590\";s:8:\"\u0000*\u0000pages\";s:0:\"\";s:7:\"\u0000*\u0000issn\";s:9:\"0031-6970\";s:8:\"\u0000*\u0000eissn\";s:0:\"\";s:9:\"\u0000*\u0000aulast\";s:5:\"PRESS\";s:10:\"\u0000*\u0000aufirst\";s:8:\"Rogier R\";s:9:\"\u0000*\u0000auinit\";s:0:\"\";s:10:\"\u0000*\u0000auinitm\";s:0:\"\";s:5:\"\u0000*\u0000au\";a:7:{i:0;s:15:\"PLOEGER, Bart A\";i:1;s:16:\"DEN HARTIGH, Jan\";i:2;s:19:\"VAN DER STRAATEN, T\";i:3;s:14:\"VAN PELT, Hans\";i:4;s:16:\"DANHOF, Meindert\";i:5;s:15:\"DE FIJTER, Hans\";i:6;s:19:\"GUCHELAAR, Henk-Jan\";}s:9:\"\u0000*\u0000aucorp\";s:0:\"\";s:7:\"\u0000*\u0000isbn\";s:0:\"\";s:8:\"\u0000*\u0000coden\";s:0:\"\";s:8:\"\u0000*\u0000genre\";s:7:\"article\";s:7:\"\u0000*\u0000part\";s:0:\"\";s:9:\"\u0000*\u0000btitle\";s:0:\"\";s:8:\"\u0000*\u0000title\";s:84:\"Explaining variability in ciclosporin exposure in adult kidney transplant recipients\";s:8:\"\u0000*\u0000place\";s:10:\"Heidelberg\";s:6:\"\u0000*\u0000pub\";s:8:\"Springer\";s:10:\"\u0000*\u0000edition\";s:0:\"\";s:9:\"\u0000*\u0000tpages\";s:2:\"12\";s:9:\"\u0000*\u0000series\";s:0:\"\";s:8:\"\u0000*\u0000proxy\";s:30:\"http:\/\/proxyout.inist.fr:8080\/\";s:12:\"\u0000*\u0000integrite\";b:1;}"
arXiv access
