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Early suppression of immune response pathways characterizes children with prediabetes in genome-wide gene expression profiling

Author
ELO, Laura L1 2 ; MYKKÄNEN, Juha1 ; KNIP, Mikael10 9 ; SIMELL, Olli3 ; LAHESMAA, Riitta1 11 ; NIKULA, Tuomas1 ; JÄRVENPÄÄ, Henna1 ; SIMELL, Satu3 ; AITTOKALLIO, Tero1 2 ; HYÖTY, Heikki5 6 ; ILONEN, Jorma4 7 ; VEIJOLA, Riitta8 ; SIMELL, Tuula3
[1] Turku Centre for Biotechnology, University of Turku and Abo Akademi University, 20521 Turku, Finland
[2] Department of Mathematics, University of Turku, 20014 Turku, Finland
[3] Department of Pediatrics, University of Turku, 20014 Turku, Finland
[4] Immunogenetics Laboratory, University of Turku, 20014 Turku, Finland
[5] Department of Virology, University of Tampere, 33014 Tampere, Finland
[6] Centre for Laboratory Medicine, University Hospital of Tampere, 33520 Tampere, Finland
[7] Department of Clinical Microbiology, University of Kuopio, 70211 Kuopio, Finland
[8] Department of Pediatrics, University of Oulu, 90014 Oulu, Finland
[9] Hospital for Children and Adolescents and Folkhälsan Research Center, University of Helsinki, 00014 Helsinki, Finland
[10] Department of Pediatrics, Tampere University Hospital, 33521 Tampere, Finland
[11] Immune Disease Institute, Harvard Medical School, Boston, MA, United States
Source

Journal of autoimmunity (Print). 2010, Vol 35, Num 1, pp 70-76, 7 p ; ref : 56 ref

ISSN
0896-8411
Scientific domain
Immunology, immunopathology, allergology
Publisher
Elsevier, Kidlington
Publication country
United Kingdom
Document type
Article
Language
English
Author keyword
Autoantibodies Differential gene expression Longitudinal data Molecular networks Pathway analysis Prediabetes Type 1 diabetes
Keyword (fr)
Anticorps Autoanticorps Autoimmunité Diabète de type 1 Enfant Expression génique Génome Immunologie Précoce Réponse immune Réseau Suppression Profil d'expression génique Endocrinopathie Homme Immunopathologie Maladie autoimmune
Keyword (en)
Antibody Autoantibody Autoimmunity Type 1 diabetes Child Gene expression Genome Immunology Early Immune response Network Suppression Gene expression profile Endocrinopathy Human Immunopathology Autoimmune disease
Keyword (es)
Anticuerpo Autoanticuerpo Autoinmunidad Diabetes de tipo 1 Niño Expresión genética Genoma Inmunología Precoz Respuesta inmune Red Supresión Perfil de expresión genética Endocrinopatía Hombre Inmunopatología Enfermedad autoinmune
Classification
Pascal
002 Biological and medical sciences / 002A Fundamental and applied biological sciences. Psychology / 002A06 Fundamental immunology

Pascal
002 Biological and medical sciences / 002B Medical sciences / 002B21 Endocrinopathies / 002B21E Endocrine pancreas. Apud cells (diseases) / 002B21E01 Diabetes. Impaired glucose tolerance / 002B21E01A Etiopathogenesis. Screening. Investigations. Target tissue resistance

Discipline
Endocrinopathies Fundamental immunology
Origin
Inist-CNRS
Database
PASCAL
INIST identifier
22858085

Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS

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