Early alterations in heart gene expression profiles associated with doxorubicin cardiotoxicity in rats
- Author
- THOMPSON, Karol L1 ; ROSENZWEIG, Barry A2 ; JUN ZHANG2 ; KNAPTON, Alan D2 ; HONCHEL, Ronald2 ; LIPSHULTZ, Steven E3 ; RETIEF, Jacques4 ; SISTARE, Frank D2 ; HERMAN, Eugene H2
[1] Center for Drug Evaluation and Research, US Food and Drug Administration, LSB64 Room 2036, 10903 New Hampshire Avenue, Silver Spring, MD 20993, United States
[2] Center for Drug Evaluation and Research, US Food and Drug Administration, 10903 New Hampshire Avenue, Silver Spring, MD 20993, United States
[3] Department of Pediatrics, Leonard M. Miller School of Medicine, University of Miami, Miami, FL, United States
[4] Affymetrix Inc., Santa Clara, CA, United States - Source
Cancer chemotherapy and pharmacology. 2010, Vol 66, Num 2, pp 303-314, 12 p ; ref : 39 ref
- CODEN
- CCPHDZ
- ISSN
- 0344-5704
- Scientific domain
- Medical oncology; Pharmacology drugs
- Publisher
- Springer, Heidelberg
- Publication country
- Germany
- Document type
- Article
- Language
- English
- Author keyword
- Anthracycline Cardioprotection Cardiotoxicity Dexrazoxane Doxorubicin Microarray
- Keyword (fr)
- Altération Animal Anthracyclines Anticancéreux Cardioprotecteur Coeur Dexrazoxane Doxorubicine Microréseau Pathologie de l'appareil circulatoire Précoce Rat Toxicité Profil d'expression génique Appareil circulatoire Chélateur DNA topoisomerase (ATP-hydrolysing) Dérivé de la pipérazine Enzyme Inhibiteur de la topoisomérase II Inhibiteur enzyme Isomerases Mammalia Rodentia Vertebrata
- Keyword (en)
- Alteration Animal Anthracyclins Antineoplastic agent Cardioprotective agent Heart Dexrazoxane Doxorubicin Microarray Cardiovascular disease Early Rat Toxicity Gene expression profile Circulatory system Chelating agent DNA topoisomerase (ATP-hydrolysing) Piperazine derivatives Enzyme Topoisomerase II inhibitor Enzyme inhibitor Isomerases Mammalia Rodentia Vertebrata
- Keyword (es)
- Alteración Animal Antraciclinas Anticanceroso Cardioprotector Corazón Dexrazoxano Doxorubicina Microarreglo Aparato circulatorio patología Precoz Rata Toxicidad Perfil de expresión genética Aparato circulatorio Quelante DNA topoisomerase (ATP-hydrolysing) Piperazina derivado Enzima Inhibidor topoisomerase II Inhibidor enzima Isomerases Mammalia Rodentia Vertebrata
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02R Antineoplastic agents
- Discipline
- Pharmacological treatments
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 22862113
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1007/s00280-009-1164-9 
https://dx.doi.org/10.1007/s00280-009-1164-9
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