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Early alterations in heart gene expression profiles associated with doxorubicin cardiotoxicity in rats

Author
THOMPSON, Karol L1 ; ROSENZWEIG, Barry A2 ; JUN ZHANG2 ; KNAPTON, Alan D2 ; HONCHEL, Ronald2 ; LIPSHULTZ, Steven E3 ; RETIEF, Jacques4 ; SISTARE, Frank D2 ; HERMAN, Eugene H2
[1] Center for Drug Evaluation and Research, US Food and Drug Administration, LSB64 Room 2036, 10903 New Hampshire Avenue, Silver Spring, MD 20993, United States
[2] Center for Drug Evaluation and Research, US Food and Drug Administration, 10903 New Hampshire Avenue, Silver Spring, MD 20993, United States
[3] Department of Pediatrics, Leonard M. Miller School of Medicine, University of Miami, Miami, FL, United States
[4] Affymetrix Inc., Santa Clara, CA, United States
Source

Cancer chemotherapy and pharmacology. 2010, Vol 66, Num 2, pp 303-314, 12 p ; ref : 39 ref

CODEN
CCPHDZ
ISSN
0344-5704
Scientific domain
Medical oncology; Pharmacology drugs
Publisher
Springer, Heidelberg
Publication country
Germany
Document type
Article
Language
English
Author keyword
Anthracycline Cardioprotection Cardiotoxicity Dexrazoxane Doxorubicin Microarray
Keyword (fr)
Altération Animal Anthracyclines Anticancéreux Cardioprotecteur Coeur Dexrazoxane Doxorubicine Microréseau Pathologie de l'appareil circulatoire Précoce Rat Toxicité Profil d'expression génique Appareil circulatoire Chélateur DNA topoisomerase (ATP-hydrolysing) Dérivé de la pipérazine Enzyme Inhibiteur de la topoisomérase II Inhibiteur enzyme Isomerases Mammalia Rodentia Vertebrata
Keyword (en)
Alteration Animal Anthracyclins Antineoplastic agent Cardioprotective agent Heart Dexrazoxane Doxorubicin Microarray Cardiovascular disease Early Rat Toxicity Gene expression profile Circulatory system Chelating agent DNA topoisomerase (ATP-hydrolysing) Piperazine derivatives Enzyme Topoisomerase II inhibitor Enzyme inhibitor Isomerases Mammalia Rodentia Vertebrata
Keyword (es)
Alteración Animal Antraciclinas Anticanceroso Cardioprotector Corazón Dexrazoxano Doxorubicina Microarreglo Aparato circulatorio patología Precoz Rata Toxicidad Perfil de expresión genética Aparato circulatorio Quelante DNA topoisomerase (ATP-hydrolysing) Piperazina derivado Enzima Inhibidor topoisomerase II Inhibidor enzima Isomerases Mammalia Rodentia Vertebrata
Classification
Pascal
002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02R Antineoplastic agents

Discipline
Pharmacological treatments
Origin
Inist-CNRS
Database
PASCAL
INIST identifier
22862113

Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS

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