(-)-N-Formylanonaine from Michelia alba as a human tyrosinase inhibitor and antioxidant

Author

WANG, Hui-Min¹ ; CHEN, Chung-Yi² ; CHEN, Chun-Yen³ ; HO, Mei-Ling⁴ ; CHOU, Yi-Ting⁴ ; CHANG, Hou-Chien⁵ ; LEE, Chih-Hung⁶ ; WANG, Chau-Zen⁴ ; CHU, I-Ming⁷
[1] Department of Fragrance and Cosmetic Science, Kaohsiung Medical University, Kaohsiung 807, Taiwan, Province of China
[2] School of Medicine and Health Sciences, Fooyin University, Kaohsiung County 831, Taiwan, Province of China
[3] Department of Chemical Engineering, National Cheng Kung University, Tainan 701, Taiwan, Province of China
[4] Department of Physiology, Kaohsiung Medical University, Orthopaedic Research Center, and the Department of Orthopaedics, Kaohsiung Medical University Hospital, Kaohsiung 807, Taiwan, Province of China
[5] Department of Chemical Engineering, National Chung Hsing University, Taichung 402, Taiwan, Province of China
[6] Department of Dermatology, Kaohsiung Medical University College of Medicine and Kaohsiung Municipal Hsiao-Kang Hospital, Kaohsiung 807, Taiwan, Province of China
[7] Department of Chemical Engineering, National Tsing Hua University, Hsinchu 300, Taiwan, Province of China

Source

Bioorganic & medicinal chemistry. 2010, Vol 18, Num 14, pp 5241-5247, 7 p

ISSN

0968-0896

Scientific domain

Biochemistry, molecular biology, biophysics; Pharmacology drugs

Publisher

Elsevier, Amsterdam

Publication country

Netherlands

Document type

Article

Language

English

Author keyword

(-)-N-Formylanonaine Melanocyte Molecular docking Tyrosinase inhibitor

Keyword (fr)

Activité biologique Alcaloïde Antioxydant Carboxamide Complexe enzyme inhibiteur Composé aromatique Composé pentacyclique Cytotoxicité Fibroblaste Homme Hétérocycle oxygène azote In vitro Inhibiteur enzyme Isolement Kératinocyte Magnoliaceae Mode liaison Modèle moléculaire Modélisation Monophenol monooxygenase Mélanocyte Origine végétale Peau Pharmacognosie Plante médicinale Teneur émission Toxicité Anonaïne dérivé Antityrosinase Aporphine dérivé Dibenzo[de,g]quinoléine dérivé Dibenzoquinoléine Michelia alba Angiospermae Dicotyledones Enzyme Oxidoreductases Spermatophyta

Keyword (en)

Biological activity Alkaloid Antioxidant Carboxamide Inhibitor enzyme complex Aromatic compound Pentacyclic compound Cytotoxicity Fibroblast Human Oxygen nitrogen heterocycle In vitro Enzyme inhibitor Isolation Keratinocyte Magnoliaceae Binding mode Molecular model Modeling Monophenol monooxygenase Melanocyte Plant origin Skin Pharmacognosy Medicinal plant Emission content Toxicity Angiospermae Dicotyledones Enzyme Oxidoreductases Spermatophyta

Keyword (es)

Actividad biológica Alcaloide Antioxidante Carboxamida Complejo enzima inhibidor Compuesto aromático Compuesto pentacíclico Citotoxicidad Fibroblasto Hombre Heterociclo oxígeno nitrógeno In vitro Inhibidor enzima Aislamiento Queratinocito Magnoliaceae Modo de enlace Modelo molecular Modelización Monophenol monooxygenase Melanocito Origen vegetal Piel Farmacognosia Planta medicinal Contenido emisión Toxicidad Angiospermae Dicotyledones Enzima Oxidoreductases Spermatophyta

Classification

Pascal

002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02A General pharmacology / 002B02A04 Pharmacognosy. Homeopathy. Health food

Discipline

General pharmacology

Origin

Inist-CNRS

Database

PASCAL

INIST identifier

23054872

Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS