Biological, clinical and population relevance of 95 loci for blood lipids
- Author
- TESLOVICH, Tanya M1 ; MUSUNURU, Kiran2 3 4 5 6 ; JOHANSEN, Christopher T15 ; FOUCHIER, Sigrid W16 ; ISAACS, Aaron17 ; PELOSO, Gina M18 19 ; BARBALIC, Maja20 ; RICKETTS, Sally L21 ; BIS, Joshua C22 ; AULCHENKO, Yurii S17 ; THORLEIFSSON, Gudmar23 ; FEITOSA, Mary F24 ; SMITH, Albert V7 8 ; CHAMBERS, John25 ; ORHO-MELANDER, Marju; MELANDER, Olle; JOHNSON, Toby; XIAOHUI LI; XIUQING GUO; MINGYAO LI10 9 ; YOON SHIN CHO; MIN JIN GO; YOUNG JIN KIM; EDMONDSON, Andrew C10 9 ; LEE, Jong-Young; PARK, Taesung; KYUNGA KIM; XUELING SIM; ONG, Rick Twee-Hee; CROTEAU-CHONKA, Damien C; LANGE, Leslie A; SMITH, Joshua D; SONG, Kijoung; JING HUA ZHAO; STYLIANOU, Loannis M10 ; XIN YUAN; JIAN'AN LUAN; LAMLNA, Claudia; ZIEGLER, Andreas; WEIHUA ZHANG25 ; ZEE, Robert Y. L14 4 ; WRIGHT, Alan F; WITTEMAN, Jacqueline C. M17 ; WILSON, James F; WILLEMSEN, Gonneke; KOSEKI, Masahiro11 ; WICHMANN, H.-Erich; WHITFIELD, John B; WATERWORTH, Dawn M; WAREHAM, Nicholas J; WAEBER, Gerard; VOLLENWEIDER, Peter; VOIGHT, Benjamin F2 5 ; VITART, Veronique; UITTERLINDEN, Andre G17 ; UDA, Manuela; PIRRUCCELLO, James P2 5 6 ; RIPATTI, Samuli12 13 ; CHASMAN, Daniel I14 4 ; WILLER, Cristen J1
[1] Center for Statistical Genetics, Department of Biostatistics, University of Michigan, Ann Arbor, Michigan 48109, United States
[2] Center for Human Genetic Research, Massachusetts General Hospital, Boston, Massachusetts 02114, United States
[3] Cardiovascular Research Center, Massachusetts General Hospital, Boston, Massachusetts 02114, United States
[4] Department of Medicine, Harvard Medical School, Boston, Massachusetts 02115, United States
[5] Broad Institute, Cambridge, Massachusetts 02142, United States
[6] Johns Hopkins University School of Medicine, Baltimore, Maryland 21287, United States
[7] Icelandic Heart Association, Heart Preventive Clinic and Research Institute, 201 Kopavogur, Iceland
[8] University of Iceland, 101 Reykjavik, Iceland
[9] Cardiovascular Institute, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104, United States
[10] Institute for Translational Medicine and Therapeutics, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104, United States
[11] Division of Molecular Medicine, Department of Medicine, Columbia University, New York, New York 10032, United States
[12] Institute for Molecular Medicine Finland FIMM, University of Helsinki, 00014 Helsinki, Finland
[13] National Institute for Health and Welfare, P.O. Box 104, 00251 Helsinki, Finland
[14] Division of Preventive Medicine, Brigham and Women's Hospital, Boston Massachusetts 02215, United States
[15] Robarts Research Institute, University of Western Ontario, London, Ontario N6A 5K8, Canada
[16] Department of Vascular Medicine, Academic Medical Centre at the University of Amsterdam, 1105 AZ Amsterdam, Netherlands
[17] Department of Epidemiology, Erasmus University Medical Center, P.O. Box 2040, 3000 CA Rotterdam, Netherlands
[18] Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts 02118, United States
[19] National Heart, Lung and Blood Institute's Framingham Heart Study, Framingham, Massachusetts 01702, United States
[20] Human Genetics Center, University of Texas Health Science Center at Houston, Houston, Texas 77030, United States
[21] Department of Public Health and Primary Care, Strangeways Research Laboratory, University of Cambridge, Cambridge CB1 8RN, United Kingdom
[22] Cardiovascular Health Research Unit and Department of Medicine, University of Washington, Seattle, Washington 98101, United States
[23] deCODE Genetics, 101 Reykjavik, Iceland
[24] Division of Statistical Genomics in the Center for Genome Sciences. Washington University School of Medicine, St Louis, Missouri 63108, United States
[25] Department of Epidemiology and Public Health, Imperial College London, London W21PG, United Kingdom - Source
Nature (London). 2010, Vol 466, Num 7307, pp 707-713, 7 p ; ref : 20 ref
- CODEN
- NATUAS
- ISSN
- 0028-0836
- Scientific domain
- Multidisciplinary
- Publisher
- Nature Publishing Group, London
- Publication country
- United Kingdom
- Document type
- Article
- Language
- English
- Keyword (fr)
- Animal Cardiopathie coronaire Européen Génotype Lipémie Polymorphisme mononucléotide Souris Variabilité génétique Ascendance Mammalia Pathologie de l'appareil circulatoire Rodentia Vertebrata
- Keyword (en)
- Animal Coronary heart disease European Genotype Lipemia Single nucleotide polymorphism Mouse Genetic variability Mammalia Cardiovascular disease Rodentia Vertebrata
- Keyword (es)
- Animal Cardiopatía coronaria Europeo Genotipo Lipemia Polimorfismo mononucleótido Ratón Variabilidad genética Mammalia Aparato circulatorio patología Rodentia Vertebrata
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B12 Cardiology. Vascular system / 002B12A Heart / 002B12A03 Coronary heart disease
- Discipline
- Cardiology. Circulatory system
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 23061278
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1038/nature09270 
https://dx.doi.org/10.1038/nature09270
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arXiv access
