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2-Methoxystypandrone represses RANKL-mediated osteoclastogenesis by down-regulating formation of TRAF6-TAK1 signalling complexes

Author
CHIOU, W. F1 2 ; LIAO, J. F3 ; HUANG, C. Y3 ; CHEN, C. C4
[1] National Research Institute of Chinese Medicine, Taipei, Taiwan, Province of China
[2] Institute of Life Science, National Taitung University, Taitung, Taiwan, Province of China
[3] Department of Pharmacology, National Yang-Ming University, Taipei, Taiwan, Province of China
[4] Department of Biotechnology, Hungkuang University, Taichung, Taiwan, Province of China
Source

British journal of pharmacology. 2010, Vol 161, Num 2, pp 321-335, 15 p ; ref : 1 p.1/4

CODEN
BJPCBM
ISSN
0007-1188
Scientific domain
Pharmacology drugs
Publisher
Nature Publishing Group, Basingstoke
Publication country
United Kingdom
Document type
Article
Language
English
Author keyword
2-methoxystypandrone DC-STAMP MMP-9 NF-κB NFATc1 TAK1 TRAF6 bone resorption c-Fos osteoclastogenesis
Keyword (fr)
Facteur transcription NFκB Gène fos Gène immédiat précoce Gène onc cellulaire Metalloendopeptidases Os Protooncogène Résorption Enzyme Hydrolases Peptidases Système ostéoarticulaire
Keyword (en)
Transcription factor NFκB fos Gene Immediate early gene C-Onc gene Metalloendopeptidases Bone Protooncogene Resorption Enzyme Hydrolases Peptidases Osteoarticular system
Keyword (es)
Factor transcripción NFκB Gen fos Gen inmediato precoz Gen onc celular Metalloendopeptidases Hueso Protooncogen Resorción Enzima Hydrolases Peptidases Sistema osteoarticular
Classification
Pascal
002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments

Discipline
General pharmacology
Origin
Inist-CNRS
Database
PASCAL
INIST identifier
23179410

Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS

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