Design, synthesis, and pharmacological effects of structurally simple ligands for MT1 and MT2 melatonin receptors
- Author
- CARACCI, Alessia1 ; CATALANO, Alessia1 ; LOVECE, Angelo1 ; LENTINI, Giovanni1 ; DURANTI, Andrea2 ; LUCINI, Valeria3 ; PANNACCI, Marilou3 ; SCAGLIONE, Francesco3 ; FRANCHINI, Carlo1
[1] Dipartimento Farmaco-Chimico, Università degli Studi di Bari, Via E. Orabona 4, 70126 Bari, Italy
[2] Dipartimento di Scienze del Farmaco e della Salute, Università degli Studi di Urbino 'Carlo Bo', Piazza del Rinascimento 6, 61029 Urbino, Italy
[3] Dipartimento di Farmacologia, Chemioterapia e Tossicologia Medica, Università degli Studi di Milano, Via Vanvitelli 32, 20129 Milano, Italy - Source
Bioorganic & medicinal chemistry. 2010, Vol 18, Num 17, pp 6496-6511, 16 p ; ref : 58 ref
- ISSN
- 0968-0896
- Scientific domain
- Biochemistry, molecular biology, biophysics; Pharmacology drugs
- Publisher
- Elsevier, Amsterdam
- Publication country
- Netherlands
- Document type
- Article
- Language
- English
- Author keyword
- Bioisosteres MT1 and MT2 receptors Melatonin Phenoxyalkyl amides
- Keyword (fr)
- Affinité Agoniste partiel Agoniste Carboxamide Composé aliphatique Composé monocyclique Dérivé du benzène Dérivé du cyclopropane Ether In vitro Relation structure activité Récepteur mélatonine MT1 Récepteur mélatonine MT2 Sulfure organique Synthèse chimique Acétamide dérivé Bioisostère Butyramide dérivé Cyclopropanecarboxamide dérivé
- Keyword (en)
- Affinity Partial agonist Agonist Carboxamide Aliphatic compound Monocyclic compound Benzene derivatives Cyclopropane derivatives Ether In vitro Structure activity relation MT1 melatonin receptor MT2 melatonin receptor Organic sulfide Chemical synthesis
- Keyword (es)
- Afinidad Agonista parcial Agonista Carboxamida Compuesto alifático Compuesto monocíclico Benceno derivado Ciclopropano derivado Eter In vitro Relación estructura actividad Receptor melatonina MT1 Receptor melatonina MT2 Sulfuro orgánico Síntesis química
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02B Neuropharmacology / 002B02B09 Neurotransmitters. Neurotransmission. Receptors / 002B02B09F Peptidergic system (neuropeptide, opioid peptide, opiates...). Adenosinergic and purinergic systems
- Discipline
- Pharmacological treatments
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 23195081
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1016/j.bmc.2010.06.100 
https://dx.doi.org/10.1016/j.bmc.2010.06.100
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