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Early life inorganic lead exposure induces testicular teratoma and renal and urinary bladder preneoplasia in adult metallothionein-knockout mice but not in wild type mice

Author
TOKAR, Erik J1 2 ; DIWAN, Bhalchandra A3 ; WAALKES, Michael P1 2
[1] Inorganic Carcinogenesis Section, Laboratory of Comparative Carcinogenesis, National Cancer Institute at the National Institute of Environmental Health Sciences, Research Triangle Park, NC27709, United States
[2] National Toxicology Program, the National Institute of Environmental Health Sciences, Research Triangle Park, NC27709, United States
[3] Basic Science Program, SAIC-Frederick, National Cancer Institute at Frederick, Frederick, MD 21702, United States
Source

Toxicology (Amsterdam). 2010, Vol 276, Num 1, pp 5-10, 6 p ; ref : 3/4 p

CODEN
TXICDD
ISSN
0300-483X
Scientific domain
Toxicology
Publisher
Elsevier, Kidlington
Publication country
United Kingdom
Document type
Article
Language
English
Author keyword
Carcinogenesis Lead Metallothionein Mice Testes
Keyword (fr)
Animal adulte Animal nouveau né Carcinogenèse Etude comparative Exposition Métallothionéine Plomb Précoce Rein Souris knockout Testicule Toxicité Tératome Vessie urinaire Type sauvage Appareil génital mâle Appareil urinaire Métal lourd Tumeur
Keyword (en)
Adult animal Newborn animal Carcinogenesis Comparative study Exposure Metallothionein Lead Early Kidney Knockout mouse Testicle Toxicity Teratoma Urinary bladder Wild type Male genital system Urinary system Heavy metal Tumor
Keyword (es)
Animal adulto Animal recién nacido Carcinogénesis Estudio comparativo Exposición Metalotioneina Plomo Precoz Riñón Ratón knockout Testículo Toxicidad Teratoma Vejiga Tipo salvaje Aparato genital macho Aparato urinario Metal pesado Tumor
Classification
Pascal
002 Biological and medical sciences / 002B Medical sciences / 002B03 Toxicology / 002B03L Chemical and industrial products toxicology. Toxic occupational diseases / 002B03L05 Metals and various inorganic compounds

Pascal
002 Biological and medical sciences / 002B Medical sciences / 002B04 Tumors / 002B04E Carcinogenesis, carcinogens and anticarcinogens / 002B04E02 Chemical agents

Discipline
Toxicology Tumours
Origin
Inist-CNRS
Database
PASCAL
INIST identifier
23218362

Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS

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