Design and synthesis of new adamantyl-substituted antileishmanial ether phospholipids
- Author
- PAPANASTASIOU, Loannis1 ; PROUSIS, Kyriakos C2 ; GEORGIKOPOULOU, Kalliopi2 ; PAVLIDIS, Theofilos3 ; SCOULICA, Effie3 ; KOLOCOURIS, Nicolas1 ; CALOGEROPOULOU, Theodora2
[1] Faculty of Pharmacy, Department of Pharmaceutical Chemistry, University of Athens, Panepistimioupoli-Zografou, Athens 15771, Greece
[2] Institute of Organic and Pharmaceutical Chemistry, National Hellenic Research Foundation, 48 Vassileos Constantinou Avenue, Athens 11635, Greece
[3] Department of Clinical Bacteriology, Parasitology, Zoonoses and Geographical Medicine, School of Medicine, University of Crete, Heraklion 71409, Greece - Source
Bioorganic & medicinal chemistry letters (Print). 2010, Vol 20, Num 18, pp 5484-5487, 4 p ; ref : 21 ref
- ISSN
- 0960-894X
- Scientific domain
- Biochemistry, molecular biology, biophysics; Pharmacology drugs
- Publisher
- Elsevier, Amsterdam
- Publication country
- Netherlands
- Document type
- Article
- Language
- English
- Author keyword
- Antiparasitic Ether phospholipids Leishmania infantum Miltefosine
- Keyword (fr)
- Amastigote Antiparasitaire Antiprotozoaire Cytotoxicité Ether Homme In vitro Leishmania infantum Leucocyte Lignée cellulaire Macrophage Miltéfosine Phospholipide Relation structure activité Synthèse chimique Toxicité Adamantane dérivé Lignée THP1 Kinetoplastida Lipide complexe Lysophospholipide Protozoa
- Keyword (en)
- Amastigote Parasiticide Antiprotozoal agent Cytotoxicity Ether Human In vitro Leishmania infantum Leukocyte Cell line Macrophage Miltefosine Phospholipid Structure activity relation Chemical synthesis Toxicity Kinetoplastida Complex lipid Lysophospholipid Protozoa
- Keyword (es)
- Amastigota Antiparasitario Antiprotozoario Citotoxicidad Eter Hombre In vitro Leishmania infantum Leucocito Línea celular Macrófago Miltefosina Fosfolípido Relación estructura actividad Síntesis química Toxicidad Kinetoplastida Lípido complejo Lisofosfolípido Protozoa
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02S Antibiotics. Antiinfectious agents. Antiparasitic agents / 002B02S06 Antiparasitic agents
- Discipline
- Pharmacological treatments
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 23248291
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1016/j.bmcl.2010.07.078 
https://dx.doi.org/10.1016/j.bmcl.2010.07.078
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