Preladenant, a selective A2A receptor antagonist, is active in primate models of movement disorders
- Author
- HODGSON, Robert A1 ; BEDARD, Paul J2 ; DARE, Aurelie2 ; NEUSTADT, Bernard R4 ; STAMFORD, Andrew W4 ; HUNTER, John C5 ; VARTY, Geoffrey B1 ; KAZDOBA, Tatiana M1 ; DI PAOLO, Therese3 ; GRZELAK, Michael E1 ; POND, Annamarie J1 ; HADJTAHAR, Abdallah2 ; BELANGER, Nancy2 ; GREGOIRE, Laurent2 3
[1] Department of Neurobiology, Merck and Co. Inc., 2015 Galloping Hill Road, Kenilworth, NJ 07033, United States
[2] Neuroscience Research Unit, Laval University Medical Center, CHUL Pavilion and Faculty of Medicine, Laval University, Quebec, Canada
[3] Molecular Endocrinology and Oncology Research Center, Laval University Medical Center (CHUL), Quebec, Canada
[4] Department of Chemical Research, Merck and Co. Inc., 2015 Galloping Hill Road, Kenilworth, NJ 07033, United States
[5] Department of Neurobiology, Merck and Co. Inc. 770 Sumneytown Pike, West Point, PA 19486, United States - Source
Experimental neurology (Print). 2010, Vol 225, Num 2, pp 384-390, 7 p ; ref : 3/4 p
- Publisher
- Elsevier, Amsterdam
- Publication country
- Netherlands
- Document type
- Article
- Language
- English
- Author keyword
- A2A Adenosine Extrapyramidal Syndrome MPTP Monkey Movement disorder Parkinson's Disease Preladenant
- Keyword (fr)
- Adénosine Animal Maladie de Parkinson Modèle Pathologie du système nerveux Primates Récepteur biologique Singe Syndrome extrapyramidal Maladie dégénérative Mammalia Pathologie de l'encéphale Pathologie du système nerveux central Vertebrata
- Keyword (en)
- Adenosine Animal Parkinson disease Models Nervous system diseases Primates Biological receptor Monkey Extrapyramidal syndrome Degenerative disease Mammalia Cerebral disorder Central nervous system disease Vertebrata
- Keyword (es)
- Adenosina Animal Parkinson enfermedad Modelo Sistema nervioso patología Primates Receptor biológico Mono Extrapiramidal síndrome Enfermedad degenerativa Mammalia Encéfalo patología Sistema nervosio central patología Vertebrata
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B17 Neurology / 002B17A Nervous system (semeiology, syndromes) / 002B17A01 Nervous system as a whole
- Discipline
- Neurology
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 23268998
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1016/j.expneurol.2010.07.011 
https://dx.doi.org/10.1016/j.expneurol.2010.07.011
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