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Early heart failure in the SMNΔ7 model of spinal muscular atrophy and correction by postnatal scAAV9-SMN delivery

Author
BEVAN, Adam K1 3 ; HUTCHINSON, Kirk R2 5 ; KASPAR, Brian K1 3 4 ; FOUST, Kevin D1 ; BRAUN, Lyndsey1 ; MCGOVERN, Vicki L4 ; SCHMELZER, Leah1 ; WARD, Jennifer G6 ; PETRUSKA, Jeffrey C7 8 ; LUCCHESI, Pamela A2 ; BURGHES, Arthur H. M3 4
[1] Department of Gene Therapy, The Research Institute, United States
[2] The Center for Cardiovascular and Pulmonary Research and The Heart Center, Nationwide Children's Hospital, Columbus, OH 43205, United States
[3] Integrated Biomedical Sciences Graduate Program, United States
[4] Department of Molecular and Cellular Biochemistry, The Ohio State University, Columbus, OH 43210, United States
[5] Department of Pharmacology and Experimental Therapeutics, Louisiana State University Health Sciences Center, New Orleans, LA, United States
[6] Specialty VETPATH, Seattle, WA 98103, United States
[7] Department of Anatomical Sciences & Neurobiology, United States
[8] Kentucky Spinal Cord Injury Research Center, Department of Neurological Surgery, University of Louisville, Louisville, KY 40292, United States
Source

Human molecular genetics (Print). 2010, Vol 19, Num 20, pp 3895-3905, 11 p ; ref : 44 ref

ISSN
0964-6906
Scientific domain
Genetics
Publisher
Oxford University Press, Oxford
Publication country
United Kingdom
Document type
Article
Language
English
Keyword (fr)
Amyotrophie médullaire Génétique Insuffisance cardiaque Modèle Pathologie du système nerveux central Postnatal Précoce Cardiopathie Maladie dégénérative Pathologie de l'appareil circulatoire Pathologie de la moelle épinière Pathologie du système nerveux Pathologie neuromusculaire
Keyword (en)
Spinal amyotrophy Genetics Heart failure Models Central nervous system disease Postnatal Early Heart disease Degenerative disease Cardiovascular disease Spinal cord disease Nervous system diseases Neuromuscular diseases
Keyword (es)
Amiotrofía medular Genética Insuficiencia cardíaca Modelo Sistema nervosio central patología Postnatal Precoz Cardiopatía Enfermedad degenerativa Aparato circulatorio patología Médula espinal patología Sistema nervioso patología Neuromuscular patología
Classification
Pascal
002 Biological and medical sciences / 002A Fundamental and applied biological sciences. Psychology / 002A04 Molecular and cellular biology

Pascal
002 Biological and medical sciences / 002A Fundamental and applied biological sciences. Psychology / 002A07 Genetics of eukaryotes. Biological and molecular evolution

Pascal
002 Biological and medical sciences / 002B Medical sciences / 002B12 Cardiology. Vascular system / 002B12A Heart / 002B12A01 Heart failure, cardiogenic pulmonary edema, cardiac enlargement

Discipline
Cardiology. Circulatory system Eukaryotes genetics. Biological and molecular evolution Molecular and cell biology
Origin
Inist-CNRS
Database
PASCAL
INIST identifier
23288553

Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS

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