PR02000 vaginal gel for prevention of HIV-1 infection (Microbicides Development Programme 301): a phase 3, randomised, double-blind, parallel-group trial
- Author
- MCCORMACK, Sheena1 ; RAMJEE, Gita2 ; MUTEMWA, Richard11 ; VALLELY, Andrew12 ; PALANEE, Thesla13 ; SOOKRAJH, Yuki2 ; LACEY, Charles J14 ; DARBYSHIRE, Janet15 ; GROSSKURTH, Heiner3 ; PROFY, Albert4 ; NUNN, Andrew5 ; HAYES, Richard1 ; KAMALI, Anatoli3 ; WEBER, Jonathan1 ; REES, Helen4 ; CROOK, Angela M5 ; GAFOS, Mitzy6 ; JENTSCH, Ute7 ; POOL, Robert8 ; CHISEMBELE, Maureen9 ; KAPIGA, Saidi10
[1] MRC Clinical Trials Unit, London, United Kingdom
[2] MRC HIV Prevention Research Unit, Durban, South Africa
[3] MRC/UVRI Uganda Research Unit, Entebbe, Uganda
[4] Reproductive Health and Research Unit, University of the Witwatersrand, Johannesburg, South Africa
[5] Contract Laboratory Services, University of the Witwatersrand, Johannesburg, South Africa
[6] Africa Centre for Health and Population Studies, Mtubatuba, South Africa
[7] University of Barcelona, Barcelona, Spain
[8] University of Amsterdam, Amsterdam, Netherlands
[9] University Teaching Hospital, Lusaka, Zambia
[10] Mwanza Intervention Trials Unit, Mwanza, Tanzania, United Republic of
[11] London School of Hygiene and Tropical Medicine, London, United Kingdom
[12] African Medical Research Foundation (AMREF), Mwanza, Tanzania, United Republic of
[13] University of York, York, United Kingdom
[14] Endo Pharmaceuticals Solutions, Chadds Ford, PA, United States
[15] Imperial College, London, United Kingdom - Source
Lancet (British edition). 2010, Vol 376, Num 9749, pp 1329-1337, 9 p ; ref : 28 ref
- CODEN
- LANCAO
- ISSN
- 0140-6736
- Scientific domain
- General medicine general surgery
- Publisher
- Elsevier, Kidlington
- Publication country
- United Kingdom
- Document type
- Article
- Language
- English
- Keyword (fr)
- Antimicrobien Chimioprophylaxie Développement Essai clinique Etude double insu Médecine Phase Randomisation SIDA Vagin Virus HIV1 Microbicide Immunodéficit Immunopathologie Infection Lentivirus Retroviridae Virose Virus immunodéficience humaine Virus
- Keyword (en)
- Antimicrobial agent Chemoprophylaxis Development Clinical trial Double blind study Medicine Phase Randomization AIDS Vagina HIV-1 virus Microbicide Immune deficiency Immunopathology Infection Lentivirus Retroviridae Viral disease Human immunodeficiency virus Virus
- Keyword (es)
- Antimicrobiano Quimioprofilaxis Desarrollo Ensayo clínico Estudio doble ciego Medicina Fase Aleatorización SIDA Vagina HIV-1 virus Inmunodeficiencia Inmunopatología Infección Lentivirus Retroviridae Virosis Human immunodeficiency virus Virus
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B05 Infectious diseases / 002B05C Viral diseases / 002B05C02 Human viral diseases / 002B05C02D Viral diseases of the lymphoid tissue and the blood. Aids
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B06 Immunopathology / 002B06D Immunodeficiencies. Immunoglobulinopathies / 002B06D01 Immunodeficiencies
- Discipline
- Generalities in medical sciences Immunopathology Infectious pathology
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 23336434
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
Access to the document
Install on your browser
DOI
10.1016/S0140-6736(10)61086-0 
https://dx.doi.org/10.1016/S0140-6736(10)61086-0
"O:13:\"PanistOpenUrl\":36:{s:10:\"\u0000*\u0000openUrl\";N;s:6:\"\u0000*\u0000idc\";N;s:6:\"\u0000*\u0000fmt\";s:7:\"journal\";s:6:\"\u0000*\u0000doi\";s:29:\"10.1016\/S0140-6736(10)61086-0\";s:6:\"\u0000*\u0000pii\";s:0:\"\";s:7:\"\u0000*\u0000pmid\";s:0:\"\";s:9:\"\u0000*\u0000atitle\";s:153:\"PR02000 vaginal gel for prevention of HIV-1 infection (Microbicides Development Programme 301): a phase 3, randomised, double-blind, parallel-group trial\";s:9:\"\u0000*\u0000jtitle\";s:24:\"Lancet (British edition)\";s:9:\"\u0000*\u0000stitle\";s:16:\"Lancet (Br. ed.)\";s:7:\"\u0000*\u0000date\";s:4:\"2010\";s:9:\"\u0000*\u0000volume\";s:3:\"376\";s:8:\"\u0000*\u0000issue\";s:4:\"9749\";s:8:\"\u0000*\u0000spage\";s:4:\"1329\";s:8:\"\u0000*\u0000epage\";s:4:\"1337\";s:8:\"\u0000*\u0000pages\";s:0:\"\";s:7:\"\u0000*\u0000issn\";s:9:\"0140-6736\";s:8:\"\u0000*\u0000eissn\";s:0:\"\";s:9:\"\u0000*\u0000aulast\";s:9:\"MCCORMACK\";s:10:\"\u0000*\u0000aufirst\";s:6:\"Sheena\";s:9:\"\u0000*\u0000auinit\";s:0:\"\";s:10:\"\u0000*\u0000auinitm\";s:0:\"\";s:5:\"\u0000*\u0000au\";a:20:{i:0;s:12:\"RAMJEE, Gita\";i:1;s:16:\"MUTEMWA, Richard\";i:2;s:15:\"VALLELY, Andrew\";i:3;s:15:\"PALANEE, Thesla\";i:4;s:14:\"SOOKRAJH, Yuki\";i:5;s:16:\"LACEY, Charles J\";i:6;s:17:\"DARBYSHIRE, Janet\";i:7;s:18:\"GROSSKURTH, Heiner\";i:8;s:13:\"PROFY, Albert\";i:9;s:12:\"NUNN, Andrew\";i:10;s:14:\"HAYES, Richard\";i:11;s:15:\"KAMALI, Anatoli\";i:12;s:15:\"WEBER, Jonathan\";i:13;s:11:\"REES, Helen\";i:14;s:15:\"CROOK, Angela M\";i:15;s:12:\"GAFOS, Mitzy\";i:16;s:12:\"JENTSCH, Ute\";i:17;s:12:\"POOL, Robert\";i:18;s:19:\"CHISEMBELE, Maureen\";i:19;s:13:\"KAPIGA, Saidi\";}s:9:\"\u0000*\u0000aucorp\";s:0:\"\";s:7:\"\u0000*\u0000isbn\";s:0:\"\";s:8:\"\u0000*\u0000coden\";s:6:\"LANCAO\";s:8:\"\u0000*\u0000genre\";s:7:\"article\";s:7:\"\u0000*\u0000part\";s:0:\"\";s:9:\"\u0000*\u0000btitle\";s:0:\"\";s:8:\"\u0000*\u0000title\";s:153:\"PR02000 vaginal gel for prevention of HIV-1 infection (Microbicides Development Programme 301): a phase 3, randomised, double-blind, parallel-group trial\";s:8:\"\u0000*\u0000place\";s:10:\"Kidlington\";s:6:\"\u0000*\u0000pub\";s:8:\"Elsevier\";s:10:\"\u0000*\u0000edition\";s:0:\"\";s:9:\"\u0000*\u0000tpages\";s:1:\"9\";s:9:\"\u0000*\u0000series\";s:0:\"\";s:8:\"\u0000*\u0000proxy\";s:30:\"http:\/\/proxyout.inist.fr:8080\/\";s:12:\"\u0000*\u0000integrite\";b:1;}"
Panist access
"O:12:\"IstexOpenUrl\":35:{s:10:\"\u0000*\u0000openUrl\";N;s:6:\"\u0000*\u0000fmt\";s:7:\"journal\";s:6:\"\u0000*\u0000doi\";s:29:\"10.1016\/S0140-6736(10)61086-0\";s:6:\"\u0000*\u0000pii\";s:0:\"\";s:7:\"\u0000*\u0000pmid\";s:0:\"\";s:9:\"\u0000*\u0000atitle\";s:153:\"PR02000 vaginal gel for prevention of HIV-1 infection (Microbicides Development Programme 301): a phase 3, randomised, double-blind, parallel-group trial\";s:9:\"\u0000*\u0000jtitle\";s:24:\"Lancet (British edition)\";s:9:\"\u0000*\u0000stitle\";s:16:\"Lancet (Br. ed.)\";s:7:\"\u0000*\u0000date\";s:4:\"2010\";s:9:\"\u0000*\u0000volume\";s:3:\"376\";s:8:\"\u0000*\u0000issue\";s:4:\"9749\";s:8:\"\u0000*\u0000spage\";s:4:\"1329\";s:8:\"\u0000*\u0000epage\";s:4:\"1337\";s:8:\"\u0000*\u0000pages\";s:0:\"\";s:7:\"\u0000*\u0000issn\";s:9:\"0140-6736\";s:8:\"\u0000*\u0000eissn\";s:0:\"\";s:9:\"\u0000*\u0000aulast\";s:9:\"MCCORMACK\";s:10:\"\u0000*\u0000aufirst\";s:6:\"Sheena\";s:9:\"\u0000*\u0000auinit\";s:0:\"\";s:10:\"\u0000*\u0000auinitm\";s:0:\"\";s:5:\"\u0000*\u0000au\";a:20:{i:0;s:12:\"RAMJEE, Gita\";i:1;s:16:\"MUTEMWA, Richard\";i:2;s:15:\"VALLELY, Andrew\";i:3;s:15:\"PALANEE, Thesla\";i:4;s:14:\"SOOKRAJH, Yuki\";i:5;s:16:\"LACEY, Charles J\";i:6;s:17:\"DARBYSHIRE, Janet\";i:7;s:18:\"GROSSKURTH, Heiner\";i:8;s:13:\"PROFY, Albert\";i:9;s:12:\"NUNN, Andrew\";i:10;s:14:\"HAYES, Richard\";i:11;s:15:\"KAMALI, Anatoli\";i:12;s:15:\"WEBER, Jonathan\";i:13;s:11:\"REES, Helen\";i:14;s:15:\"CROOK, Angela M\";i:15;s:12:\"GAFOS, Mitzy\";i:16;s:12:\"JENTSCH, Ute\";i:17;s:12:\"POOL, Robert\";i:18;s:19:\"CHISEMBELE, Maureen\";i:19;s:13:\"KAPIGA, Saidi\";}s:9:\"\u0000*\u0000aucorp\";s:0:\"\";s:7:\"\u0000*\u0000isbn\";s:0:\"\";s:8:\"\u0000*\u0000coden\";s:6:\"LANCAO\";s:8:\"\u0000*\u0000genre\";s:7:\"article\";s:7:\"\u0000*\u0000part\";s:0:\"\";s:9:\"\u0000*\u0000btitle\";s:0:\"\";s:8:\"\u0000*\u0000title\";s:153:\"PR02000 vaginal gel for prevention of HIV-1 infection (Microbicides Development Programme 301): a phase 3, randomised, double-blind, parallel-group trial\";s:8:\"\u0000*\u0000place\";s:10:\"Kidlington\";s:6:\"\u0000*\u0000pub\";s:8:\"Elsevier\";s:10:\"\u0000*\u0000edition\";s:0:\"\";s:9:\"\u0000*\u0000tpages\";s:1:\"9\";s:9:\"\u0000*\u0000series\";s:0:\"\";s:8:\"\u0000*\u0000proxy\";s:30:\"http:\/\/proxyout.inist.fr:8080\/\";s:12:\"\u0000*\u0000integrite\";b:1;}"
Istex access
"O:16:\"UnpaywallOpenUrl\":35:{s:8:\"\u0000*\u0000email\";s:27:\"assistance-portail@inist.fr\";s:6:\"\u0000*\u0000fmt\";N;s:6:\"\u0000*\u0000doi\";s:29:\"10.1016\/S0140-6736(10)61086-0\";s:6:\"\u0000*\u0000pii\";N;s:7:\"\u0000*\u0000pmid\";N;s:9:\"\u0000*\u0000atitle\";N;s:9:\"\u0000*\u0000jtitle\";N;s:9:\"\u0000*\u0000stitle\";N;s:7:\"\u0000*\u0000date\";N;s:9:\"\u0000*\u0000volume\";N;s:8:\"\u0000*\u0000issue\";N;s:8:\"\u0000*\u0000spage\";N;s:8:\"\u0000*\u0000epage\";N;s:8:\"\u0000*\u0000pages\";N;s:7:\"\u0000*\u0000issn\";N;s:8:\"\u0000*\u0000eissn\";N;s:9:\"\u0000*\u0000aulast\";N;s:10:\"\u0000*\u0000aufirst\";N;s:9:\"\u0000*\u0000auinit\";N;s:10:\"\u0000*\u0000auinitm\";N;s:5:\"\u0000*\u0000au\";N;s:9:\"\u0000*\u0000aucorp\";N;s:7:\"\u0000*\u0000isbn\";N;s:8:\"\u0000*\u0000coden\";N;s:8:\"\u0000*\u0000genre\";N;s:7:\"\u0000*\u0000part\";N;s:9:\"\u0000*\u0000btitle\";N;s:8:\"\u0000*\u0000title\";N;s:8:\"\u0000*\u0000place\";N;s:6:\"\u0000*\u0000pub\";N;s:10:\"\u0000*\u0000edition\";N;s:9:\"\u0000*\u0000tpages\";N;s:9:\"\u0000*\u0000series\";N;s:8:\"\u0000*\u0000proxy\";s:30:\"http:\/\/proxyout.inist.fr:8080\/\";s:12:\"\u0000*\u0000integrite\";N;}"
Unpaywall access
"O:16:\"EuropePMCOpenUrl\":35:{s:10:\"\u0000*\u0000openUrl\";N;s:6:\"\u0000*\u0000fmt\";s:7:\"journal\";s:6:\"\u0000*\u0000doi\";s:29:\"10.1016\/S0140-6736(10)61086-0\";s:6:\"\u0000*\u0000pii\";s:0:\"\";s:7:\"\u0000*\u0000pmid\";s:0:\"\";s:9:\"\u0000*\u0000atitle\";s:153:\"PR02000 vaginal gel for prevention of HIV-1 infection (Microbicides Development Programme 301): a phase 3, randomised, double-blind, parallel-group trial\";s:9:\"\u0000*\u0000jtitle\";s:24:\"Lancet (British edition)\";s:9:\"\u0000*\u0000stitle\";s:16:\"Lancet (Br. ed.)\";s:7:\"\u0000*\u0000date\";s:4:\"2010\";s:9:\"\u0000*\u0000volume\";s:3:\"376\";s:8:\"\u0000*\u0000issue\";s:4:\"9749\";s:8:\"\u0000*\u0000spage\";s:4:\"1329\";s:8:\"\u0000*\u0000epage\";s:4:\"1337\";s:8:\"\u0000*\u0000pages\";s:0:\"\";s:7:\"\u0000*\u0000issn\";s:9:\"0140-6736\";s:8:\"\u0000*\u0000eissn\";s:0:\"\";s:9:\"\u0000*\u0000aulast\";s:9:\"MCCORMACK\";s:10:\"\u0000*\u0000aufirst\";s:6:\"Sheena\";s:9:\"\u0000*\u0000auinit\";s:0:\"\";s:10:\"\u0000*\u0000auinitm\";s:0:\"\";s:5:\"\u0000*\u0000au\";a:20:{i:0;s:12:\"RAMJEE, Gita\";i:1;s:16:\"MUTEMWA, Richard\";i:2;s:15:\"VALLELY, Andrew\";i:3;s:15:\"PALANEE, Thesla\";i:4;s:14:\"SOOKRAJH, Yuki\";i:5;s:16:\"LACEY, Charles J\";i:6;s:17:\"DARBYSHIRE, Janet\";i:7;s:18:\"GROSSKURTH, Heiner\";i:8;s:13:\"PROFY, Albert\";i:9;s:12:\"NUNN, Andrew\";i:10;s:14:\"HAYES, Richard\";i:11;s:15:\"KAMALI, Anatoli\";i:12;s:15:\"WEBER, Jonathan\";i:13;s:11:\"REES, Helen\";i:14;s:15:\"CROOK, Angela M\";i:15;s:12:\"GAFOS, Mitzy\";i:16;s:12:\"JENTSCH, Ute\";i:17;s:12:\"POOL, Robert\";i:18;s:19:\"CHISEMBELE, Maureen\";i:19;s:13:\"KAPIGA, Saidi\";}s:9:\"\u0000*\u0000aucorp\";s:0:\"\";s:7:\"\u0000*\u0000isbn\";s:0:\"\";s:8:\"\u0000*\u0000coden\";s:6:\"LANCAO\";s:8:\"\u0000*\u0000genre\";s:7:\"article\";s:7:\"\u0000*\u0000part\";s:0:\"\";s:9:\"\u0000*\u0000btitle\";s:0:\"\";s:8:\"\u0000*\u0000title\";s:153:\"PR02000 vaginal gel for prevention of HIV-1 infection (Microbicides Development Programme 301): a phase 3, randomised, double-blind, parallel-group trial\";s:8:\"\u0000*\u0000place\";s:10:\"Kidlington\";s:6:\"\u0000*\u0000pub\";s:8:\"Elsevier\";s:10:\"\u0000*\u0000edition\";s:0:\"\";s:9:\"\u0000*\u0000tpages\";s:1:\"9\";s:9:\"\u0000*\u0000series\";s:0:\"\";s:8:\"\u0000*\u0000proxy\";s:30:\"http:\/\/proxyout.inist.fr:8080\/\";s:12:\"\u0000*\u0000integrite\";b:1;}"
Europe PubMed Central access
"O:12:\"ArXivOpenUrl\":35:{s:10:\"\u0000*\u0000openUrl\";N;s:6:\"\u0000*\u0000fmt\";s:7:\"journal\";s:6:\"\u0000*\u0000doi\";s:29:\"10.1016\/S0140-6736(10)61086-0\";s:6:\"\u0000*\u0000pii\";s:0:\"\";s:7:\"\u0000*\u0000pmid\";s:0:\"\";s:9:\"\u0000*\u0000atitle\";s:153:\"PR02000 vaginal gel for prevention of HIV-1 infection (Microbicides Development Programme 301): a phase 3, randomised, double-blind, parallel-group trial\";s:9:\"\u0000*\u0000jtitle\";s:24:\"Lancet (British edition)\";s:9:\"\u0000*\u0000stitle\";s:16:\"Lancet (Br. ed.)\";s:7:\"\u0000*\u0000date\";s:4:\"2010\";s:9:\"\u0000*\u0000volume\";s:3:\"376\";s:8:\"\u0000*\u0000issue\";s:4:\"9749\";s:8:\"\u0000*\u0000spage\";s:4:\"1329\";s:8:\"\u0000*\u0000epage\";s:4:\"1337\";s:8:\"\u0000*\u0000pages\";s:0:\"\";s:7:\"\u0000*\u0000issn\";s:9:\"0140-6736\";s:8:\"\u0000*\u0000eissn\";s:0:\"\";s:9:\"\u0000*\u0000aulast\";s:9:\"MCCORMACK\";s:10:\"\u0000*\u0000aufirst\";s:6:\"Sheena\";s:9:\"\u0000*\u0000auinit\";s:0:\"\";s:10:\"\u0000*\u0000auinitm\";s:0:\"\";s:5:\"\u0000*\u0000au\";a:20:{i:0;s:12:\"RAMJEE, Gita\";i:1;s:16:\"MUTEMWA, Richard\";i:2;s:15:\"VALLELY, Andrew\";i:3;s:15:\"PALANEE, Thesla\";i:4;s:14:\"SOOKRAJH, Yuki\";i:5;s:16:\"LACEY, Charles J\";i:6;s:17:\"DARBYSHIRE, Janet\";i:7;s:18:\"GROSSKURTH, Heiner\";i:8;s:13:\"PROFY, Albert\";i:9;s:12:\"NUNN, Andrew\";i:10;s:14:\"HAYES, Richard\";i:11;s:15:\"KAMALI, Anatoli\";i:12;s:15:\"WEBER, Jonathan\";i:13;s:11:\"REES, Helen\";i:14;s:15:\"CROOK, Angela M\";i:15;s:12:\"GAFOS, Mitzy\";i:16;s:12:\"JENTSCH, Ute\";i:17;s:12:\"POOL, Robert\";i:18;s:19:\"CHISEMBELE, Maureen\";i:19;s:13:\"KAPIGA, Saidi\";}s:9:\"\u0000*\u0000aucorp\";s:0:\"\";s:7:\"\u0000*\u0000isbn\";s:0:\"\";s:8:\"\u0000*\u0000coden\";s:6:\"LANCAO\";s:8:\"\u0000*\u0000genre\";s:7:\"article\";s:7:\"\u0000*\u0000part\";s:0:\"\";s:9:\"\u0000*\u0000btitle\";s:0:\"\";s:8:\"\u0000*\u0000title\";s:153:\"PR02000 vaginal gel for prevention of HIV-1 infection (Microbicides Development Programme 301): a phase 3, randomised, double-blind, parallel-group trial\";s:8:\"\u0000*\u0000place\";s:10:\"Kidlington\";s:6:\"\u0000*\u0000pub\";s:8:\"Elsevier\";s:10:\"\u0000*\u0000edition\";s:0:\"\";s:9:\"\u0000*\u0000tpages\";s:1:\"9\";s:9:\"\u0000*\u0000series\";s:0:\"\";s:8:\"\u0000*\u0000proxy\";s:30:\"http:\/\/proxyout.inist.fr:8080\/\";s:12:\"\u0000*\u0000integrite\";b:1;}"
arXiv access
