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Antihypertensive activity of newer 1,4-dihydro-5-pyrimidine carboxamides: Synthesis and pharmacological evaluation

Author
ALAM, Ozair1 ; KHAN, Suroor A1 ; SIDDIQUI, Nadeem1 ; AHSAN, Waquar1 ; VERMA, Suraj P1 ; GILANI, Sadaf J1
[1] Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Hamdard University, Hamdard Nagar, New Delhi 110062, India
Source

European journal of medicinal chemistry. 2010, Vol 45, Num 11, pp 5113-5119, 7 p ; ref : 13 ref

CODEN
EJMCA5
ISSN
0223-5234
Scientific domain
Organic chemistry; Pharmacology drugs
Publisher
Elsevier, Kidlington
Publication country
United Kingdom
Document type
Article
Language
English
Author keyword
Antihypertensive activity DOCA-salt Dihydropyridine Dihydropyrimidine
Keyword (fr)
Animal Antihypertenseur Carboxamide Chimiothérapie Dérivé du benzène Hypertension artérielle Hétérocycle azote Pathologie expérimentale Rat Relation structure activité Synthèse chimique Voie orale Pyrimidine-5-carboxamide(4-aryl-N-aryl-2-arylméthylsulfanyl-6-méthyl) Mammalia Pathologie de l'appareil circulatoire Rodentia Traitement Vertebrata
Keyword (en)
Animal Antihypertensive agent Carboxamide Chemotherapy Benzene derivatives Hypertension Nitrogen heterocycle Experimental disease Rat Structure activity relation Chemical synthesis Oral administration Mammalia Cardiovascular disease Rodentia Treatment Vertebrata
Keyword (es)
Animal Antihipertensivo Carboxamida Quimioterapia Benceno derivado Hipertensión arterial Heterociclo nitrógeno Patología experimental Rata Relación estructura actividad Síntesis química Vía oral Mammalia Aparato circulatorio patología Rodentia Tratamiento Vertebrata
Classification
Pascal
002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02F Cardiovascular system / 002B02F05 Antihypertensive agents

Discipline
Pharmacological treatments
Origin
Inist-CNRS
Database
PASCAL
INIST identifier
23367532

Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS

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