Synthesis and pharmacological evaluation of clubbed isopropylthiazole derived triazolothiadiazoles, triazolothiadiazines and mannich bases as potential antimicrobial and antitubercular agents
- Author
- SURESH KUMAR, G. V1 ; RAJENDRA PRASAD, Y2 ; MALLIKARJUNA, B. P3 ; CHANDRASHEKAR, S. M4
[1] St Johns Pharmacy College, Department of Medicinal Chemistry, 6, 2nd stage Vijaynagar, R.P.C. Layout, Bangalore 560040, Karnataka, India
[2] University College of Pharmaceutical Sciences, Andhra University, Visakhapatnam 530003, Andhra Pradesh, India
[3] PES College of Pharmacy, Department of Medicinal Chemistry, 50 feet road, Hanumantha nagar, B.S.K. Ist stage, Bangalore 560050, Kamataka, India
[4] St Johns Pharmacy College, Department of Medicinal Chemistry, 6, 2nd stage Vijaynagar, R.P.C Layout, Bangalore 560040, Karnataka, India - Source
European journal of medicinal chemistry. 2010, Vol 45, Num 11, pp 5120-5129, 10 p ; ref : 31 ref
- CODEN
- EJMCA5
- ISSN
- 0223-5234
- Scientific domain
- Organic chemistry; Pharmacology drugs
- Publisher
- Elsevier, Kidlington
- Publication country
- United Kingdom
- Document type
- Article
- Language
- English
- Author keyword
- 4-Isopropylthiazole Cytotoxicity Mannich bases Mtitubercular Triazolothiadiazines Triazolothiadiazoles
- Keyword (fr)
- Anticancéreux Antifongique Antimicrobien Antituberculeux Base Mannich Cellule tumorale Composé bicyclique Cycle 5 chaînons Cytotoxicité Dérivé du thiazole Homme Hétérocycle azote Hétérocycle soufre azote In vitro Lignée cellulaire Mycobacterium tuberculosis Poumon Relation structure activité Synthèse chimique 1,2,4-Triazole-5-thione dérivé 1,2,4-Triazolo[3,4-b]-1,3,4-thiadiazole dérivé 1,2,4-Triazolo[3,4-b][1,3,4]thiadiazine dérivé Lignée A549 Triazolothiadiazine Triazolothiadiazole Actinomycetes Bactérie Mycobacteriaceae Mycobacteriales
- Keyword (en)
- Antineoplastic agent Antifungal agent Antimicrobial agent Antituberculous agent Mannich base Tumor cell Bicyclic compound Five membered ring Cytotoxicity Thiazole derivatives Human Nitrogen heterocycle Sulfur nitrogen heterocycle In vitro Cell line Mycobacterium tuberculosis Lung Structure activity relation Chemical synthesis Actinomycetes Bacteria Mycobacteriaceae Mycobacteriales
- Keyword (es)
- Anticanceroso Antifúngico Antimicrobiano Antituberculoso Base Mannich Célula tumoral Compuesto bicíclico Ciclo 5 eslabones Citotoxicidad Tiazol derivado Hombre Heterociclo nitrógeno Heterociclo azufre nitrógeno In vitro Línea celular Mycobacterium tuberculosis Pulmón Relación estructura actividad Síntesis química Actinomycetes Bacteria Mycobacteriaceae Mycobacteriales
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02R Antineoplastic agents / 002B02R01 General aspects
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02S Antibiotics. Antiinfectious agents. Antiparasitic agents / 002B02S01 General aspects
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02S Antibiotics. Antiinfectious agents. Antiparasitic agents / 002B02S02 Antibacterial agents
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02S Antibiotics. Antiinfectious agents. Antiparasitic agents / 002B02S04 Antifungal agents
- Discipline
- Pharmacological treatments
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 23367533
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1016/j.ejmech.2010.08.023 
https://dx.doi.org/10.1016/j.ejmech.2010.08.023
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