Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution
- Author
- HEID, Iris M1 2 ; JACKSON, Anne U3 ; WORKALEMAHU, Tsegaselassie5 ; WHITE, Charles C12 ; BOUATIA-NAJI, Nabila13 14 ; HARRIS, Tamara B15 ; BERNDT, Sonja I16 ; INGELSSON, Erik17 ; WILLER, Cristen J3 ; WEEDON, Michael N18 ; JIAN'AN LUAN19 ; VEDANTAM, Sailaja10 20 ; RANDALL, Joshua C4 ; ESKO, Tõnu21 22 23 ; KILPELÄINEN, Tuomas O19 ; KUTALIK, Zoltán24 25 ; SHENGXU LI19 ; MONDA, Keri L; DIXON, Anna L; HOLMES, Christopher C; KAPLAN, Lee M11 ; LIMING LIANG; MIN, Josine L; WINKLER, Thomas W1 ; MOFFATT, Miriam F; MOLONY, Cliona; NICHOLSON, George; SCHADT, Eric E; ZONDERVAN, Krina T; FEITOSA, Mary F; FERREIRA, Teresa4 ; LANGO ALLEN, Hana18 ; WEYANT, Robert J3 ; WHEELER, Eleanor; LU QI5 6 ; WOOD, Andrew R18 ; MAGIC; ESTRADA, Karol8 9 ; GODDARD, Michael E; LETTRE, Guillaume; MANGINO, Massimo; NYHOLT, Dale R; PURCELL, Shaun; VERNON SMITH, Albert; VISSCHER, Peter M; STEINTHORSDOTTIR, Valgerdur7 ; JIAN YANG; MCCARROLL, Steven A; NEMESH, James; VOIGHT, Benjamin F; ABSHER, Devin; AMIN, Najaf; ASPELUND, Thor; COIN, Lachlan; GLAZER, Nicole L; HAYWARD, Caroline; THORLEIFSSON, Gudmar7 ; CAROLA ZILLIKENS, M8 9 ; SPELIOTES, Elizabeth K10 11 ; MÄGI, Reedik4
[1] Regensburg University Medical Center, Department of Epidemiology and Preventive Medicine, Regensburg, Germany
[2] Institute of Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany
[3] Department of Biostatistics, Center for Statistical Genetics, University of Michigan, Ann Arbor, Michigan, United States
[4] Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom
[5] Department of Nutrition, Harvard School of Public Health, Boston, Massachusetts, United States
[6] Channing Laboratory, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, United States
[7] deCODE Genetics, Reykjavik, Iceland
[8] Department of Internal Medicine, Erasmus Medical Center (MC), Rotterdam, Netherlands
[9] Netherlands Genomics Initiative (NGI)-sponsored Netherlands Consortium for Healthy Aging (NCHA), Rotterdam, Netherlands
[10] Metabolism Initiative and Program in Medical and Population Genetics, Broad Institute, Cambridge, Massachusetts, United States
[11] Division of Gastroenterology, Massachusetts General Hospital, Boston, Massachusetts, United States
[12] Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts, United States
[13] Centre National de la Recherche Scientifique (CNRS), UMR8199-IBL-Institut Pasteur de Lille, Lille, France
[14] University Lille Nord de France, Lille, France
[15] Laboratory of Epidemiology, Demography, Biometry, National Institute on Aging, National Institutes of Health, Bethesda, Maryland, United States
[16] Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, Maryland, United States
[17] Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden
[18] Genetics of Complex Traits, Peninsula College of Medicine and Dentistry, University of Exeter, Exeter, United Kingdom
[19] Medical Research Council (MRC) Epidemiology Unit, Institute of Metabolic Science, Addenbrooke's Hospital, Cambridge, United Kingdom
[20] Divisions of Genetics and Endocrinology and Program in Genomics, Children's Hospital, Boston, Massachusetts, United States
[21] Estonian Genome Center, University of Tartu, Tartu, Estonia
[22] Estonian Biocenter, Tartu, Estonia
[23] Institute of Molecular and Cell Biology, University of Tartu, Tartu, Estonia
[24] Department of Medical Genetics, University of Lausanne, Lausanne, Switzerland
[25] Swiss Institute of Bioinformatics, Lausanne, Switzerland - Source
Nature genetics. 2010, Vol 42, Num 11, pp 949-960, 12 p ; ref : 49 ref
- Publisher
- Nature Publishing Group, New York, NY
- Publication country
- United States
- Document type
- Article
- Language
- English
- Keyword (fr)
- Dimorphisme sexuel Distribution Génétique Hanche Identification Locus Matière grasse Métaanalyse
- Keyword (en)
- Sexual dimorphism Distribution Genetics Hip Identification Locus Fat Metaanalysis
- Keyword (es)
- Dimorfismo sexual Distribución Genética Cadera Identificación Locus Materia grasa Meta-análisis
- Classification
- Pascal
- 002 Biological and medical sciences / 002A Fundamental and applied biological sciences. Psychology / 002A07 Genetics of eukaryotes. Biological and molecular evolution
- Discipline
- Eukaryotes genetics. Biological and molecular evolution
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 23404650
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1038/ng.685 
https://dx.doi.org/10.1038/ng.685
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arXiv access
