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Binding of factor VIII to von Willebrand factor is enabled by cleavage of the von Willebrand factor propeptide and enhanced by formation of disulfide-linked multimers

Author
BENDETOWICZ, A. V; MORRIS, J. A; WISE, R. J; GILBERT, G. E; KAUFMAN, R. J
Brigham and Women's Hospital, Boston, MA, United States
Brockton/West Roxbury VAMC, West Roxbury, MA, United States
Department of Biological Chemistry and the Howard Hughes Medical Institute, University of Michigan, Ann Arbor, MI, United States
Harvard University Medical School, Boston, MA, United States
Source

Blood. 1998, Vol 92, Num 2, pp 529-538 ; ref : 48 ref

ISSN
0006-4971
Scientific domain
Medical oncology; Hematology
Publisher
The Americain Society of Hematology, Washington, DC
Publication country
United States
Document type
Article
Language
English
Keyword (fr)
Animal Facteur Willebrand Facteur antihémophilique A Facteur coagulation Forme moléculaire Liaison disulfure Mode liaison Mécanisme Porc Relation structure fonction Site fixation Sérum Propeptide Artiodactyla Mammalia Ungulata Vertebrata
Keyword (en)
Animal Willebrand factor Factor VIII Coagulation factor Molecular form Disulfide bond Binding mode Mechanism Pig Structure function relationship Binding site Serum Artiodactyla Mammalia Ungulata Vertebrata
Keyword (es)
Animal Factor Willebrand Factor antihemofílico A Factor coagulación Forma molecular Enlace disulfuro Modo de enlace Mecanismo Cerdo Relación estructura función Sitio fijación Suero Artiodactyla Mammalia Ungulata Vertebrata
Classification
Pascal
002 Biological and medical sciences / 002A Fundamental and applied biological sciences. Psychology / 002A04 Molecular and cellular biology / 002A04I Blood coagulation. Blood cells / 002A04I02 Coagulation factors

Discipline
Molecular and cell biology
Origin
Inist-CNRS
Database
PASCAL
INIST identifier
2345473

Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS

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